4XDO
Crystal structure of human KDM4C catalytic domain with OGA
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 401 |
| Chain | Residue |
| A | CYS236 |
| A | HIS242 |
| A | CYS308 |
| A | CYS310 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue FE A 402 |
| Chain | Residue |
| A | HIS190 |
| A | GLU192 |
| A | HIS278 |
| A | OGA403 |
| A | HOH568 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue OGA A 403 |
| Chain | Residue |
| A | TYR134 |
| A | TYR179 |
| A | PHE187 |
| A | HIS190 |
| A | GLU192 |
| A | SER198 |
| A | ASN200 |
| A | LYS208 |
| A | HIS278 |
| A | FE402 |
| A | HOH568 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue PGE A 404 |
| Chain | Residue |
| A | ASP63 |
| A | LEU67 |
| A | ILE142 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue PGE A 406 |
| Chain | Residue |
| A | GLN90 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 401 |
| Chain | Residue |
| B | CYS236 |
| B | HIS242 |
| B | CYS308 |
| B | CYS310 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue FE B 402 |
| Chain | Residue |
| B | HIS190 |
| B | GLU192 |
| B | HIS278 |
| B | OGA403 |
| B | HOH543 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue OGA B 403 |
| Chain | Residue |
| B | TYR134 |
| B | HIS190 |
| B | GLU192 |
| B | SER198 |
| B | ASN200 |
| B | LYS208 |
| B | HIS278 |
| B | FE402 |
| B | HOH543 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue PG4 B 404 |
| Chain | Residue |
| B | ASP63 |
| B | LEU67 |
| B | SER141 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 84 |
| Details | Domain: {"description":"JmjN","evidences":[{"source":"PROSITE-ProRule","id":"PRU00537","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 332 |
| Details | Domain: {"description":"JmjC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00538","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"B2RXH2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21914792","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
