Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0005007 | molecular_function | fibroblast growth factor receptor activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0004672 | molecular_function | protein kinase activity |
B | 0004713 | molecular_function | protein tyrosine kinase activity |
B | 0005007 | molecular_function | fibroblast growth factor receptor activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | binding site for residue 66T A 801 |
Chain | Residue |
A | LEU484 |
A | TYR563 |
A | ALA564 |
A | SER565 |
A | GLY567 |
A | GLU571 |
A | LEU630 |
A | ALA640 |
A | ASP641 |
A | GLY485 |
A | ALA512 |
A | LYS514 |
A | GLU531 |
A | MET535 |
A | VAL559 |
A | VAL561 |
A | GLU562 |
site_id | AC2 |
Number of Residues | 14 |
Details | binding site for residue 66T B 801 |
Chain | Residue |
B | GLY485 |
B | ALA512 |
B | LYS514 |
B | GLU531 |
B | VAL561 |
B | GLU562 |
B | TYR563 |
B | ALA564 |
B | SER565 |
B | GLY567 |
B | LEU630 |
B | ASP641 |
B | PHE642 |
B | HOH989 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 31 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGAFGQVVlAeaigldkdkpnrvtk...VAVK |
Chain | Residue | Details |
A | LEU484-LYS514 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CIHrDLAARNVLV |
Chain | Residue | Details |
A | CYS619-VAL631 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | GLU592 | |
B | GLU592 | |
site_id | SWS_FT_FI2 |
Number of Residues | 10 |
Details | BINDING: |
Chain | Residue | Details |
A | PRO483 | |
B | GLY610 | |
A | GLU531 | |
A | MET537 | |
A | SER596 | |
A | GLY610 | |
B | PRO483 | |
B | GLU531 | |
B | MET537 | |
B | SER596 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | SITE: Mediates interaction with PLCG1 and SHB |
Chain | Residue | Details |
A | ASP735 | |
B | ASP735 | |
Chain | Residue | Details |
A | THR552 | |
A | ASP554 | |
B | THR552 | |
B | ASP554 | |
Chain | Residue | Details |
A | ARG622 | |
A | ASP623 | |
B | ARG622 | |
B | ASP623 | |
Chain | Residue | Details |
A | SER699 | |
B | SER699 | |
Chain | Residue | Details |
A | ASP735 | |
B | ASP735 | |