4W9M

AMPPNP bound Rad50 in complex with dsDNA

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0006302	biological_process	double-strand break repair
C	0016887	molecular_function	ATP hydrolysis activity
E	0006302	biological_process	double-strand break repair
E	0016887	molecular_function	ATP hydrolysis activity
I	0006302	biological_process	double-strand break repair
I	0016887	molecular_function	ATP hydrolysis activity
K	0006302	biological_process	double-strand break repair
K	0016887	molecular_function	ATP hydrolysis activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	26
Details	binding site for residue ANP C 901

Chain	Residue
C	LEU12
C	ARG53
C	TYR54
C	ASP59
C	VAL61
C	ASN62
C	ARG63
C	GLN142
C	MG902
C	HOH1013
C	HOH1015
C	GLY13
E	ARG741
E	ARG762
E	GLY766
E	SER768
E	GLY769
E	GLY770
E	GLU771
C	ASN32
C	GLY33
C	ALA34
C	GLY35
C	LYS36
C	SER37
C	SER38

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MG C 902

Chain	Residue
C	SER37
C	GLN142
C	ANP901
C	HOH1013
C	HOH1015

---

site_id	AC3
Number of Residues	26
Details	binding site for residue ANP E 901

Chain	Residue
C	ARG741
C	ARG762
C	GLY766
C	SER768
C	GLY769
C	GLY770
C	GLU771
E	LEU12
E	GLY13
E	ASN32
E	GLY33
E	ALA34
E	GLY35
E	LYS36
E	SER37
E	SER38
E	ARG53
E	TYR54
E	ASP59
E	VAL61
E	ASN62
E	ARG63
E	GLN142
E	GLU798
E	MG902
E	HOH1025

---

site_id	AC4
Number of Residues	4
Details	binding site for residue MG E 902

Chain	Residue
E	SER37
E	GLN142
E	ANP901
E	HOH1025

---

site_id	AC5
Number of Residues	26
Details	binding site for residue ANP I 901

Chain	Residue
I	LEU12
I	GLY13
I	ASN32
I	GLY33
I	ALA34
I	GLY35
I	LYS36
I	SER37
I	SER38
I	ARG53
I	TYR54
I	ASP59
I	VAL61
I	ASN62
I	ARG63
I	GLN142
I	MG902
I	HOH1005
I	HOH1030
K	ARG741
K	ARG762
K	GLY766
K	SER768
K	GLY769
K	GLY770
K	GLU771

---

site_id	AC6
Number of Residues	4
Details	binding site for residue MG I 902

Chain	Residue
I	SER37
I	GLN142
I	ANP901
I	HOH1005

---

site_id	AC7
Number of Residues	29
Details	binding site for residue ANP K 901

Chain	Residue
K	PRO31
K	ASN32
K	GLY33
K	ALA34
K	GLY35
K	LYS36
K	SER37
K	SER38
K	ARG53
K	TYR54
K	ASP59
K	VAL61
K	ASN62
K	ARG63
K	GLN142
K	GLU798
K	MG902
K	HOH1015
K	HOH1021
K	HOH1022
K	HOH1037
I	ARG762
I	GLY766
I	SER768
I	GLY769
I	GLY770
I	GLU771
K	LEU12
K	GLY13

---

site_id	AC8
Number of Residues	5
Details	binding site for residue MG K 902

Chain	Residue
K	SER37
K	GLN142
K	ANP901
K	HOH1015
K	HOH1037

---

site_id	AC9
Number of Residues	6
Details	binding site for Di-peptide LYS I 109 and ALA I 110

Chain	Residue
G	DG27
I	SER101
I	GLU102
I	LYS108
I	ALA111
I	ILE112

---

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGERALISISLAM

Chain	Residue	Details
C	LEU767-MET781

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21458667","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3QF7","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21937514","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3THO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21458667","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"21937514","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25349191","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3QF7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3THO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4W9M","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21458667","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25349191","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3QF7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4W9M","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21458667","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25349191","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3QF7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3THO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4W9M","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21458667","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"21937514","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3QF7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3THO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PDB","id":"4W9M","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---