4UYA
Structure of MLK4 kinase domain with ATPgammaS
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE AGS A 1438 |
| Chain | Residue |
| A | VAL138 |
| A | LEU270 |
| A | ASP289 |
| A | MG1439 |
| A | MG1440 |
| A | HOH2038 |
| A | ALA149 |
| A | ILE184 |
| A | LEU200 |
| A | GLU201 |
| A | ALA203 |
| A | ASP263 |
| A | LYS265 |
| A | ASN268 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 1439 |
| Chain | Residue |
| A | LYS265 |
| A | ASN268 |
| A | AGS1438 |
| A | MG1440 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 1440 |
| Chain | Residue |
| A | LYS265 |
| A | AGS1438 |
| A | MG1439 |
| A | HOH2039 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 22 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGAGGFGQVYrAtwqgqe............VAVK |
| Chain | Residue | Details |
| A | ILE130-LYS151 |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IlHrDLKssNILL |
| Chain | Residue | Details |
| A | ILE259-LEU271 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"Q02779","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q02779","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
