Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0005007 | molecular_function | fibroblast growth factor receptor activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0004672 | molecular_function | protein kinase activity |
B | 0004713 | molecular_function | protein tyrosine kinase activity |
B | 0005007 | molecular_function | fibroblast growth factor receptor activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO B 1766 |
Chain | Residue |
B | GLU531 |
B | MET535 |
B | ASP641 |
B | PHE642 |
B | GLY643 |
B | HOH2018 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 1766 |
Chain | Residue |
A | PHE642 |
A | GLY643 |
A | GLU531 |
A | ALA640 |
A | ASP641 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO B 1767 |
Chain | Residue |
B | MET535 |
B | GLY539 |
B | LYS540 |
B | ILE544 |
B | ASN546 |
B | LEU547 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 1767 |
Chain | Residue |
A | TRP684 |
A | ARG718 |
A | MET719 |
A | TRP737 |
A | HOH2066 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 1768 |
Chain | Residue |
A | ALA615 |
A | HIS679 |
A | THR746 |
A | PHE747 |
A | LYS748 |
site_id | AC6 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE JVT B 1768 |
Chain | Residue |
B | LEU484 |
B | VAL561 |
B | GLU562 |
B | ALA564 |
B | SER565 |
B | GLY567 |
B | LEU630 |
site_id | AC7 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE JVT A 1769 |
Chain | Residue |
A | LEU484 |
A | ALA512 |
A | VAL561 |
A | GLU562 |
A | ALA564 |
A | SER565 |
A | GLY567 |
A | LEU630 |
A | HOH2031 |
site_id | AC8 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 1770 |
Chain | Residue |
A | ARG570 |
A | ARG627 |
A | THR657 |
A | ASN659 |
A | ARG661 |
A | HOH2057 |
site_id | AC9 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 B 1769 |
Chain | Residue |
B | ARG570 |
B | ARG627 |
B | THR657 |
B | ASN659 |
B | ARG661 |
B | HOH2054 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 31 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGAFGQVVlAeaigldkdkpnrvtk...VAVK |
Chain | Residue | Details |
A | LEU484-LYS514 | |
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CIHrDLAARNVLV |
Chain | Residue | Details |
A | CYS619-VAL631 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP623 | |
B | ASP623 | |
site_id | SWS_FT_FI2 |
Number of Residues | 12 |
Details | BINDING: |
Chain | Residue | Details |
A | LEU484 | |
B | ASN568 | |
B | ARG627 | |
B | ASP641 | |
A | LYS514 | |
A | GLU562 | |
A | ASN568 | |
A | ARG627 | |
A | ASP641 | |
B | LEU484 | |
B | LYS514 | |
B | GLU562 | |
Chain | Residue | Details |
A | TYR463 | |
A | TYR583 | |
A | TYR585 | |
B | TYR463 | |
B | TYR583 | |
B | TYR585 | |
Chain | Residue | Details |
A | TYR653 | |
A | TYR654 | |
B | TYR653 | |
B | TYR654 | |
Chain | Residue | Details |
A | TYR730 | |
B | TYR730 | |