Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4UER

40S-eIF1-eIF1A-eIF3-eIF3j translation initiation complex from Lachancea kluyveri

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0003723	molecular_function	RNA binding
0	0003743	molecular_function	translation initiation factor activity
0	0005737	cellular_component	cytoplasm
0	0006412	biological_process	translation
0	0006413	biological_process	translational initiation
1	0000028	biological_process	ribosomal small subunit assembly
1	0003735	molecular_function	structural constituent of ribosome
1	0005840	cellular_component	ribosome
1	0006412	biological_process	translation
1	0022627	cellular_component	cytosolic small ribosomal subunit
1	0030490	biological_process	maturation of SSU-rRNA
2	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
2	0003735	molecular_function	structural constituent of ribosome
2	0005840	cellular_component	ribosome
2	0006412	biological_process	translation
2	0022627	cellular_component	cytosolic small ribosomal subunit
2	1990904	cellular_component	ribonucleoprotein complex
3	0003735	molecular_function	structural constituent of ribosome
3	0005840	cellular_component	ribosome
3	0006412	biological_process	translation
3	1990904	cellular_component	ribonucleoprotein complex
4	0003735	molecular_function	structural constituent of ribosome
4	0005737	cellular_component	cytoplasm
4	0005840	cellular_component	ribosome
4	0006412	biological_process	translation
4	0022627	cellular_component	cytosolic small ribosomal subunit
4	1990904	cellular_component	ribonucleoprotein complex
5	0003729	molecular_function	mRNA binding
5	0003735	molecular_function	structural constituent of ribosome
5	0005840	cellular_component	ribosome
5	0006412	biological_process	translation
5	0022627	cellular_component	cytosolic small ribosomal subunit
5	1990904	cellular_component	ribonucleoprotein complex
6	0000028	biological_process	ribosomal small subunit assembly
6	0003723	molecular_function	RNA binding
6	0003735	molecular_function	structural constituent of ribosome
6	0005840	cellular_component	ribosome
6	0006412	biological_process	translation
6	0022627	cellular_component	cytosolic small ribosomal subunit
6	0046872	molecular_function	metal ion binding
6	1990904	cellular_component	ribonucleoprotein complex
7	0003723	molecular_function	RNA binding
7	0003735	molecular_function	structural constituent of ribosome
7	0005737	cellular_component	cytoplasm
7	0022627	cellular_component	cytosolic small ribosomal subunit
8	0003735	molecular_function	structural constituent of ribosome
8	0005840	cellular_component	ribosome
8	0022627	cellular_component	cytosolic small ribosomal subunit
8	1990904	cellular_component	ribonucleoprotein complex
9	0003735	molecular_function	structural constituent of ribosome
9	0005840	cellular_component	ribosome
9	0006412	biological_process	translation
a	0001732	biological_process	formation of cytoplasmic translation initiation complex
a	0002183	biological_process	cytoplasmic translational initiation
a	0003723	molecular_function	RNA binding
a	0003743	molecular_function	translation initiation factor activity
a	0005737	cellular_component	cytoplasm
a	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
a	0006412	biological_process	translation
a	0006413	biological_process	translational initiation
a	0016282	cellular_component	eukaryotic 43S preinitiation complex
a	0033290	cellular_component	eukaryotic 48S preinitiation complex
b	0001732	biological_process	formation of cytoplasmic translation initiation complex
b	0002183	biological_process	cytoplasmic translational initiation
b	0003676	molecular_function	nucleic acid binding
b	0003723	molecular_function	RNA binding
b	0003743	molecular_function	translation initiation factor activity
b	0005737	cellular_component	cytoplasm
b	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
b	0006412	biological_process	translation
b	0006413	biological_process	translational initiation
b	0016282	cellular_component	eukaryotic 43S preinitiation complex
b	0031369	molecular_function	translation initiation factor binding
b	0033290	cellular_component	eukaryotic 48S preinitiation complex
B	0000028	biological_process	ribosomal small subunit assembly
B	0002181	biological_process	cytoplasmic translation
B	0003735	molecular_function	structural constituent of ribosome
B	0005737	cellular_component	cytoplasm
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0015935	cellular_component	small ribosomal subunit
B	0022627	cellular_component	cytosolic small ribosomal subunit
B	0030686	cellular_component	90S preribosome
B	1990904	cellular_component	ribonucleoprotein complex
c	0001732	biological_process	formation of cytoplasmic translation initiation complex
c	0002183	biological_process	cytoplasmic translational initiation
c	0003723	molecular_function	RNA binding
c	0003743	molecular_function	translation initiation factor activity
c	0005737	cellular_component	cytoplasm
c	0005852	cellular_component	eukaryotic translation initiation factor 3 complex
c	0006412	biological_process	translation
c	0006413	biological_process	translational initiation
c	0016282	cellular_component	eukaryotic 43S preinitiation complex
c	0031369	molecular_function	translation initiation factor binding
c	0033290	cellular_component	eukaryotic 48S preinitiation complex
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
C	0015935	cellular_component	small ribosomal subunit
C	0022626	cellular_component	cytosolic ribosome
C	1990904	cellular_component	ribonucleoprotein complex
D	0003723	molecular_function	RNA binding
D	0003735	molecular_function	structural constituent of ribosome
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0015935	cellular_component	small ribosomal subunit
D	0019843	molecular_function	rRNA binding
D	0043226	cellular_component	organelle
D	1990904	cellular_component	ribonucleoprotein complex
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0015935	cellular_component	small ribosomal subunit
E	1990904	cellular_component	ribonucleoprotein complex
F	0003743	molecular_function	translation initiation factor activity
F	0006413	biological_process	translational initiation
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005840	cellular_component	ribosome
G	0006412	biological_process	translation
G	0015935	cellular_component	small ribosomal subunit
G	1990904	cellular_component	ribonucleoprotein complex
H	0003735	molecular_function	structural constituent of ribosome
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0022627	cellular_component	cytosolic small ribosomal subunit
H	1990904	cellular_component	ribonucleoprotein complex
I	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0022627	cellular_component	cytosolic small ribosomal subunit
I	1990904	cellular_component	ribonucleoprotein complex
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0015935	cellular_component	small ribosomal subunit
J	1990904	cellular_component	ribonucleoprotein complex
K	0000028	biological_process	ribosomal small subunit assembly
K	0003735	molecular_function	structural constituent of ribosome
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0022627	cellular_component	cytosolic small ribosomal subunit
K	1990904	cellular_component	ribonucleoprotein complex
L	0003735	molecular_function	structural constituent of ribosome
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0015935	cellular_component	small ribosomal subunit
L	0022627	cellular_component	cytosolic small ribosomal subunit
L	1990904	cellular_component	ribonucleoprotein complex
M	0003676	molecular_function	nucleic acid binding
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0015935	cellular_component	small ribosomal subunit
M	1990904	cellular_component	ribonucleoprotein complex
N	0003735	molecular_function	structural constituent of ribosome
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0008270	molecular_function	zinc ion binding
N	0022627	cellular_component	cytosolic small ribosomal subunit
N	1990904	cellular_component	ribonucleoprotein complex
O	0003735	molecular_function	structural constituent of ribosome
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	1990904	cellular_component	ribonucleoprotein complex
P	0003735	molecular_function	structural constituent of ribosome
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	1990904	cellular_component	ribonucleoprotein complex
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0022627	cellular_component	cytosolic small ribosomal subunit
Q	1990904	cellular_component	ribonucleoprotein complex
R	0006417	biological_process	regulation of translation
R	0043022	molecular_function	ribosome binding
R	0045182	molecular_function	translation regulator activity
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0015935	cellular_component	small ribosomal subunit
S	1990904	cellular_component	ribonucleoprotein complex
T	0000028	biological_process	ribosomal small subunit assembly
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0022627	cellular_component	cytosolic small ribosomal subunit
T	1990904	cellular_component	ribonucleoprotein complex
U	0003735	molecular_function	structural constituent of ribosome
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	1990904	cellular_component	ribonucleoprotein complex
V	0003735	molecular_function	structural constituent of ribosome
V	0005829	cellular_component	cytosol
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	1990904	cellular_component	ribonucleoprotein complex
W	0003723	molecular_function	RNA binding
W	0003735	molecular_function	structural constituent of ribosome
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
W	0019843	molecular_function	rRNA binding
W	0022627	cellular_component	cytosolic small ribosomal subunit
W	0032991	cellular_component	protein-containing complex
W	0043229	cellular_component	intracellular organelle
W	1990904	cellular_component	ribonucleoprotein complex
X	0003735	molecular_function	structural constituent of ribosome
X	0005829	cellular_component	cytosol
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0022627	cellular_component	cytosolic small ribosomal subunit
X	1990904	cellular_component	ribonucleoprotein complex
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Z	0000461	biological_process	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005737	cellular_component	cytoplasm
Z	0005840	cellular_component	ribosome
Z	0006364	biological_process	rRNA processing
Z	0006412	biological_process	translation
Z	0022627	cellular_component	cytosolic small ribosomal subunit
Z	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN 5 101

Chain	Residue
5	CYS23
5	CYS26
5	CYS74
5	CYS77

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN 6 101

Chain	Residue
6	CYS37
6	CYS40
6	CYS56
6	CYS59

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN 9 201

Chain	Residue
9	CYS126
9	CYS141
9	CYS144
9	CYS121

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN N 101

Chain	Residue
N	CYS21
N	CYS24
N	CYS39
N	CYS42

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsLMmngrnnGKKlkavrIIkhT

Chain	Residue	Details
G	GLU91-THR117

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GyvILTTSaGIMdheeAR

Chain	Residue	Details
H	GLY100-ARG117

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GLrIgrieDvTPvPSD

Chain	Residue	Details
K	LEU102-ASP124

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
L	LYS62-ARG69

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgQcRPIS

Chain	Residue	Details
Q	GLY120-SER132

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKafnqveIrpemLGhyLGEFsiT

Chain	Residue	Details
S	ASN98-THR122

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvSQvyAirqAiAKGL

Chain	Residue	Details
I	GLY71-LEU89

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AeqhNLvkkGPVrLPT

Chain	Residue	Details
J	ALA45-THR60

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY

Chain	Residue	Details
O	VAL98-TYR128

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsshtglirkyg.LNICRqCFR

Chain	Residue	Details
N	ARG22-ARG44

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRLAaPhhWlLdK

Chain	Residue	Details
W	HIS8-LYS22

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKSvGFGlVYNSvaeakkfE

Chain	Residue	Details
P	PHE64-GLU86

site_id	PS00548
Number of Residues	37
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. AKamkfadGfLihSgqpVndfIDtatrhvlMrqGvlG

Chain	Residue	Details
C	ALA147-GLY183

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM

Chain	Residue	Details
Y	ILE52-MET63

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAvvVVGDsn.GhVGlGiktak.EVag.AI

Chain	Residue	Details
E	GLY93-ILE125

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PykhidaSgsInRkVLQaLE

Chain	Residue	Details
T	PRO90-GLU109

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVYKlglAkSvhhARvLI

Chain	Residue	Details
D	LEU105-ILE129

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGiRHfwGlrVRGQ

Chain	Residue	Details
M	ARG123-GLN136

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSAswDkTLRLWDV

Chain	Residue	Details
R	ALA80-VAL94
R	ILE169-LEU183
R	ILE211-LEU225

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. IqSKrLRNkIAGYtTH

Chain	Residue	Details
V	ILE41-HIS56

site_id	PS00733
Number of Residues	8
Details	RIBOSOMAL_S26E Ribosomal protein S26e signature. YCVSCAIH

Chain	Residue	Details
5	TYR73-HIS80

site_id	PS00948
Number of Residues	14
Details	RIBOSOMAL_S7E Ribosomal protein S7e signature. KLtRELEKKFQdRH

Chain	Residue	Details
3	LYS76-HIS89

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
1	GLU58-LEU66

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. AqLLLAANTHLG

Chain	Residue	Details
B	ALA14-GLY25

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlVIVtDprsDaqaIkEasyvNIP

Chain	Residue	Details
B	PRO118-PRO142

site_id	PS00996
Number of Residues	9
Details	RIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA

Chain	Residue	Details
Z	LEU11-ALA19

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgClnittvFShAqtavtCesCStiLctPtG

Chain	Residue	Details
6	LYS36-GLY68

site_id	PS01189
Number of Residues	19
Details	RIBOSOMAL_S12E Ribosomal protein S12e signature. ALKvvLrtAlvhDGLarGL

Chain	Residue	Details
U	ALA27-LEU45

site_id	PS01191
Number of Residues	13
Details	RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVvEvCLaDL

Chain	Residue	Details
4	LEU61-LEU73

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RsaTGAkraqf.RkKrKfELG

Chain	Residue	Details
2	ARG11-GLY30

site_id	PS01262
Number of Residues	23
Details	IF1A Eukaryotic initiation factor 1A signature. MlGnGRveasCfDGnkRmaHIrG

Chain	Residue	Details
0	MET41-GLY63

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)