Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0010468 | biological_process | regulation of gene expression |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1001 |
| Chain | Residue |
| A | CYS537 |
| A | CYS540 |
| A | CYS559 |
| A | CYS562 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1002 |
| Chain | Residue |
| A | CYS494 |
| A | CYS497 |
| A | CYS514 |
| A | CYS517 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1003 |
| Chain | Residue |
| A | CYS554 |
| A | CYS583 |
| A | CYS586 |
| A | CYS549 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue SAH A 1004 |
| Chain | Residue |
| A | PHE640 |
| A | ASP641 |
| A | ILE643 |
| A | THR645 |
| A | GLU664 |
| A | VAL665 |
| A | CYS666 |
| A | ASP686 |
| A | VAL687 |
| A | GLY707 |
| A | PRO709 |
| A | LEU730 |
| A | ARG891 |
| A | SER892 |
| A | TRP893 |
Functional Information from PROSITE/UniProt
| site_id | PS00094 |
| Number of Residues | 13 |
| Details | C5_MTASE_1 C-5 cytosine-specific DNA methylases active site. DlVigGsPCnDLS |
| Chain | Residue | Details |
| A | ASP702-SER714 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 132 |
| Details | Domain: {"description":"ADD","evidences":[{"source":"PROSITE-ProRule","id":"PRU00865","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 30 |
| Details | Zinc finger: {"description":"GATA-type; atypical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00865","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 56 |
| Details | Zinc finger: {"description":"PHD-type; atypical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00865","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 92 |
| Details | Region: {"description":"Interaction with the PRC2/EED-EZH2 complex","evidences":[{"source":"UniProtKB","id":"O88508","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01016","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10018","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17713477","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QRV","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"S-methylcysteine; by autocatalysis","evidences":[{"source":"UniProtKB","id":"O88508","evidenceCode":"ECO:0000250"}]} |
