4U2F
Crystal structure of dienelactone hydrolase B-1 variant (Q35H, F38L, Y64H, Q110L, C123S, Y137C, Y145C, N154D, E199G, S208G and G211D) at 1.80 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008806 | molecular_function | carboxymethylenebutenolidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019439 | biological_process | obsolete aromatic compound catabolic process |
| A | 0052689 | molecular_function | carboxylic ester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | MET1 |
| A | ALA72 |
| A | HOH554 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. DleaairyarHlpYSNGKVGLvGYSlGGA |
| Chain | Residue | Details |
| A | ASP99-ALA127 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | SER123 | |
| A | ASP171 | |
| A | HIS202 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 7 |
| Details | M-CSA 492 |
| Chain | Residue | Details |
| A | GLU36 | proton shuttle (general acid/base) |
| A | ILE37 | electrostatic stabiliser |
| A | TYR85 | electrostatic stabiliser |
| A | SER123 | electrostatic stabiliser |
| A | LEU124 | electrostatic stabiliser |
| A | ASP171 | electrostatic stabiliser |
| A | HIS202 | electrostatic stabiliser |
