Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009228 | biological_process | thiamine biosynthetic process |
| A | 0016830 | molecular_function | carbon-carbon lyase activity |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0009228 | biological_process | thiamine biosynthetic process |
| B | 0016830 | molecular_function | carbon-carbon lyase activity |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SF4 A 701 |
| Chain | Residue |
| A | CYS570 |
| A | MET572 |
| A | CYS573 |
| A | CYS578 |
| A | SER579 |
| A | MET580 |
| B | CL701 |
| B | SAH704 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE IRN A 702 |
| Chain | Residue |
| A | MET257 |
| A | LEU259 |
| A | TYR286 |
| A | THR320 |
| A | HIS322 |
| A | SER342 |
| A | ARG343 |
| A | GLY344 |
| A | ASP383 |
| A | ARG386 |
| A | GLU422 |
| A | GLY423 |
| A | TYR449 |
| A | LEU451 |
| A | SAH703 |
| A | HOH919 |
| A | ASN228 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE SAH A 703 |
| Chain | Residue |
| A | ASN228 |
| A | ILE229 |
| A | GLY230 |
| A | LEU259 |
| A | VAL341 |
| A | ARG343 |
| A | ARG386 |
| A | HIS426 |
| A | GLU489 |
| A | HIS490 |
| A | LEU493 |
| A | PRO494 |
| A | IRN702 |
| A | ZN704 |
| A | HOH961 |
| A | HOH1006 |
| A | HOH1007 |
| A | HOH1008 |
| A | HOH1051 |
| A | HOH1065 |
| B | MET572 |
| B | CYS573 |
| B | SF4702 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 704 |
| Chain | Residue |
| A | HIS426 |
| A | HIS490 |
| A | SAH703 |
| A | HOH961 |
| A | HOH962 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 705 |
| Chain | Residue |
| A | HIS490 |
| A | HOH963 |
| B | SF4702 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 701 |
| Chain | Residue |
| A | MET580 |
| A | SF4701 |
| B | HIS490 |
| B | HOH1066 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SF4 B 702 |
| Chain | Residue |
| A | SAH703 |
| A | CL705 |
| B | CYS570 |
| B | MET572 |
| B | CYS573 |
| B | CYS578 |
| B | SER579 |
| site_id | AC8 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE IRN B 703 |
| Chain | Residue |
| B | ASN228 |
| B | MET257 |
| B | LEU259 |
| B | TYR286 |
| B | THR320 |
| B | HIS322 |
| B | SER342 |
| B | ARG343 |
| B | GLY344 |
| B | ASP383 |
| B | ARG386 |
| B | GLU422 |
| B | GLY423 |
| B | TYR449 |
| B | LEU451 |
| B | SAH704 |
| site_id | AC9 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE SAH B 704 |
| Chain | Residue |
| B | IRN703 |
| B | ZN705 |
| B | HOH1008 |
| B | HOH1045 |
| B | HOH1054 |
| B | HOH1056 |
| B | HOH1057 |
| B | HOH1064 |
| A | MET572 |
| A | CYS573 |
| A | SF4701 |
| B | ASN228 |
| B | ILE229 |
| B | GLY230 |
| B | LEU259 |
| B | VAL341 |
| B | ARG343 |
| B | ARG386 |
| B | HIS426 |
| B | LEU451 |
| B | GLU489 |
| B | HIS490 |
| B | LEU493 |
| B | PRO494 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 705 |
| Chain | Residue |
| B | HIS426 |
| B | HIS490 |
| B | SAH704 |
| B | HOH1064 |
| B | HOH1065 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9A6Q5","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24161603","evidenceCode":"ECO:0000305"}]} |
