Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0017136 | molecular_function | NAD-dependent histone deacetylase activity |
| A | 0051287 | molecular_function | NAD binding |
| A | 0070403 | molecular_function | NAD+ binding |
| B | 0017136 | molecular_function | NAD-dependent histone deacetylase activity |
| B | 0051287 | molecular_function | NAD binding |
| B | 0070403 | molecular_function | NAD+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE AR6 A 401 |
| Chain | Residue |
| A | GLY84 |
| A | HIS187 |
| A | PHE235 |
| A | GLY261 |
| A | THR262 |
| A | SER263 |
| A | ASN286 |
| A | LYS287 |
| A | GLU288 |
| A | GLY322 |
| A | GLU323 |
| A | ALA85 |
| A | CYS324 |
| A | EDO404 |
| A | HOH504 |
| A | HOH543 |
| A | HOH549 |
| A | GLY86 |
| A | THR89 |
| A | ASP95 |
| A | PHE96 |
| A | ARG97 |
| A | TYR104 |
| A | GLN167 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NCA A 402 |
| Chain | Residue |
| A | ILE93 |
| A | PRO94 |
| A | PHE96 |
| A | ASN168 |
| A | ILE169 |
| A | ASP170 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG A 403 |
| Chain | Residue |
| A | GLU56 |
| A | SER100 |
| A | THR101 |
| A | ASN106 |
| A | PRO277 |
| A | LEU278 |
| A | SER279 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 404 |
| Chain | Residue |
| A | PHE119 |
| A | HIS187 |
| A | VAL233 |
| A | AR6401 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 405 |
| Chain | Residue |
| A | SER88 |
| A | HIS149 |
| A | ASN168 |
| A | ASP170 |
| A | GLU173 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 406 |
| Chain | Residue |
| A | CYS195 |
| A | CYS200 |
| A | CYS221 |
| A | CYS224 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 401 |
| Chain | Residue |
| B | CYS195 |
| B | CYS200 |
| B | CYS221 |
| B | CYS224 |
| site_id | AC8 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE AR6 B 402 |
| Chain | Residue |
| B | GLY84 |
| B | ALA85 |
| B | GLY86 |
| B | THR89 |
| B | ASP95 |
| B | PHE96 |
| B | ARG97 |
| B | TYR104 |
| B | GLN167 |
| B | HIS187 |
| B | PHE235 |
| B | GLY261 |
| B | THR262 |
| B | SER263 |
| B | VAL266 |
| B | ASN286 |
| B | LYS287 |
| B | GLU288 |
| B | GLY322 |
| B | GLU323 |
| B | CYS324 |
| B | EDO404 |
| B | HOH514 |
| B | HOH526 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 403 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 404 |
| Chain | Residue |
| B | HIS187 |
| B | VAL233 |
| B | AR6402 |
| B | HOH520 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PGE B 405 |
| Chain | Residue |
| B | GLN265 |
| B | GLY291 |
| B | SER293 |
| B | PHE296 |
| B | MET299 |
| B | ILE300 |
| B | MET301 |
| B | GLY304 |
| B | HOH519 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS187 | |
| B | HIS187 | |
| Chain | Residue | Details |
| A | ALA85 | |
| B | THR262 | |
| B | ASN286 | |
| B | CYS324 | |
| A | ASP95 | |
| A | GLN167 | |
| A | THR262 | |
| A | ASN286 | |
| A | CYS324 | |
| B | ALA85 | |
| B | ASP95 | |
| B | GLN167 | |
| Chain | Residue | Details |
| A | CYS195 | |
| A | CYS200 | |
| A | CYS221 | |
| A | CYS224 | |
| B | CYS195 | |
| B | CYS200 | |
| B | CYS221 | |
| B | CYS224 | |
| Chain | Residue | Details |
| A | SER100 | |
| A | SER207 | |
| B | SER100 | |
| B | SER207 | |
