4RHL
Crystal structure of T. brucei arginase-like protein triple mutant S149D/R151H/S226D bound with Mn2+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004053 | molecular_function | arginase activity |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0006525 | biological_process | arginine metabolic process |
| A | 0008783 | molecular_function | agmatinase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0020023 | cellular_component | kinetoplast |
| A | 0033389 | biological_process | putrescine biosynthetic process from arginine, via agmatine |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004053 | molecular_function | arginase activity |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0006525 | biological_process | arginine metabolic process |
| B | 0008783 | molecular_function | agmatinase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0020023 | cellular_component | kinetoplast |
| B | 0033389 | biological_process | putrescine biosynthetic process from arginine, via agmatine |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 400 |
| Chain | Residue |
| A | ASP149 |
| A | HIS151 |
| A | ASP224 |
| A | ASP226 |
| A | HOH515 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 401 |
| Chain | Residue |
| A | ASN280 |
| A | VAL281 |
| A | GLY282 |
| A | ALA285 |
| A | ARG38 |
| A | PRO40 |
| A | TYR269 |
| A | TYR276 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN B 401 |
| Chain | Residue |
| B | ASP149 |
| B | HIS151 |
| B | ASP224 |
| B | ASP226 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 402 |
| Chain | Residue |
| B | PRO40 |
| B | PHE44 |
| B | ASN280 |
| B | VAL281 |
| B | GLY282 |
