4RFE

Crystal structure of ADCC-potent ANTI-HIV-1 Rhesus macaque antibody JR4 Fab

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 H 301

Chain	Residue
C	ARG30
C	ARG31
C	TYR52
C	SER53
H	HIS50
H	ASN58
H	TRP97
H	HOH495

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL L 301

Chain	Residue
D	SER59

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL L 302

Chain	Residue
L	SER59

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL L 303

Chain	Residue
L	ASN156
L	THR157

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site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 301

Chain	Residue
B	ASN156

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site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 302

Chain	Residue
B	GLN184

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site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL D 301

Chain	Residue
D	ASN156

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site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL E 301

Chain	Residue
A	ASN32
A	TYR33
A	THR95
A	VAL96
A	TRP97
E	SER56

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site_id	AC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 E 302

Chain	Residue
A	HIS50
A	ASN58
A	TRP97
E	ARG31
E	TYR52
E	SER53
E	HOH455
E	HOH497
E	HOH525

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH

Chain	Residue	Details
L	TYR191-HIS197
H	TYR194-HIS200

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