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4RBO

Crystal structure of a Nanog homeobox (NANOG) from Homo sapiens at 3.30 A resolution

Functional Information from GO Data
ChainGOidnamespacecontents
A0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
A0003677molecular_functionDNA binding
A0006355biological_processregulation of DNA-templated transcription
D0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
D0003677molecular_functionDNA binding
D0006355biological_processregulation of DNA-templated transcription
Functional Information from PROSITE/UniProt
site_idPS00027
Number of Residues24
DetailsHOMEOBOX_1 'Homeobox' domain signature. LSniLnLSykQVKTWFqNqrmksK
ChainResidueDetails
ALEU128-LYS151

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues58
DetailsRegion: {"description":"Required for DNA-binding","evidences":[{"source":"PubMed","id":"25825768","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

246905

PDB entries from 2025-12-31

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