Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 801 |
| Chain | Residue |
| A | ARG616 |
| A | THR646 |
| A | ASN648 |
| A | ARG650 |
| A | HOH945 |
| A | HOH946 |
| A | HOH974 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE 0LI A 802 |
| Chain | Residue |
| A | VAL502 |
| A | LYS503 |
| A | GLU520 |
| A | MET524 |
| A | VAL550 |
| A | GLU551 |
| A | CYS552 |
| A | ALA553 |
| A | LEU603 |
| A | CYS608 |
| A | ILE609 |
| A | HIS610 |
| A | ARG611 |
| A | LEU619 |
| A | ILE628 |
| A | ALA629 |
| A | ASP630 |
| A | PHE631 |
| A | LEU633 |
| A | VAL481 |
| A | ALA501 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 803 |
| Chain | Residue |
| A | ARG563 |
| A | ARG566 |
| A | SER688 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 804 |
| Chain | Residue |
| A | LYS555 |
| A | GLU622 |
| A | ASP623 |
| A | ASN624 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 805 |
| Chain | Residue |
| A | ARG707 |
| A | TRP726 |
| A | HIS727 |
| A | ALA728 |
| A | HOH938 |
| A | HOH989 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 31 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGAFGQVVrAeafgmdparpdqast...VAVK |
| Chain | Residue | Details |
| A | LEU473-LYS503 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CIHrDLAARNVLV |
| Chain | Residue | Details |
| A | CYS608-VAL620 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"18670643","evidenceCode":"ECO:0000269"}]} |
