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4PKL

Bromodomain of Trypanosoma brucei BDF2 With IBET-151

Functional Information from PDB Data
site_idAC1
Number of Residues14
Detailsbinding site for residue 1GH A 201
ChainResidue
ALEU28
AGLN109
AHOH321
AHOH348
AHOH388
BGLN94
AGLY29
AMET30
AVAL35
AGLU39
ATYR85
AASN86
ATRP92
AASP105

site_idAC2
Number of Residues8
Detailsbinding site for residue PO4 A 202
ChainResidue
ATRP23
AHIS32
AHIS33
AHOH352
AHOH391
AHOH432
AHOH435
BHOH397

site_idAC3
Number of Residues6
Detailsbinding site for residue K A 203
ChainResidue
ALEU83
AGLU84
AASN86
AHOH360
AHOH420
BHOH334

site_idAC4
Number of Residues2
Detailsbinding site for residue CL A 204
ChainResidue
ALYS88
AHOH380

site_idAC5
Number of Residues15
Detailsbinding site for residue 1GH B 201
ChainResidue
ALEU16
AVAL19
ASER20
ATRP23
AARG57
AHOH302
BLEU28
BGLY29
BMET30
BGLU39
BLEU40
BASN86
BTRP92
BHOH365
BHOH373

site_idAC6
Number of Residues6
Detailsbinding site for residue K B 202
ChainResidue
AHOH341
BLEU83
BGLU84
BASN86
BHOH348
BHOH391

site_idAC7
Number of Residues7
Detailsbinding site for residue GOL B 203
ChainResidue
AASP24
ALYS27
BGLY29
BHIS32
BHIS33
BHOH318
BHOH390

Functional Information from PROSITE/UniProt
site_idPS00633
Number of Residues53
DetailsBROMODOMAIN_1 Bromodomain signature. HpvSaeelP.......DYHtvIkrpVdlssIrdgiekgt..Yatdvdvqndvar.MitNAleY
ChainResidueDetails
AHIS33-TYR85

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PDB entries from 2024-11-06

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