4P7I

Crystal structure of the Merlin FERM/DCAF1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003779	molecular_function	actin binding
A	0005856	cellular_component	cytoskeleton
A	0008092	molecular_function	cytoskeletal protein binding
B	0003779	molecular_function	actin binding
B	0005856	cellular_component	cytoskeleton
B	0008092	molecular_function	cytoskeletal protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue GOL A 401

Chain	Residue
A	ARG52
A	THR53
A	ASP245

---

Functional Information from PROSITE/UniProt

site_id	PS00660
Number of Residues	31
Details	FERM_1 FERM domain signature 1. WLkmdKkVldHd.Vskeepvt.FhflakFYpeN

Chain	Residue	Details
A	TRP74-ASN104

---

site_id	PS00661
Number of Residues	30
Details	FERM_2 FERM domain signature 2. YaehrgrardEAemeYLki.AqdLemYGvNY

Chain	Residue	Details
A	TYR192-TYR221

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:24275569

Chain	Residue	Details
C	ASP1449
D	ASP1449

---