4P5E
CRYSTAL STRUCTURE OF HUMAN DNPH1 (RCL) WITH 6-NAPHTHYL-PURINE-RIBOSIDE-MONOPHOSPHATE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009159 | biological_process | deoxyribonucleoside monophosphate catabolic process |
| A | 0070694 | molecular_function | 5-hydroxymethyl-dUMP N-hydrolase activity |
| B | 0009159 | biological_process | deoxyribonucleoside monophosphate catabolic process |
| B | 0070694 | molecular_function | 5-hydroxymethyl-dUMP N-hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue N6P A 201 |
| Chain | Residue |
| A | CYS26 |
| A | ILE76 |
| A | ASP80 |
| A | SER98 |
| A | GLY100 |
| A | GLU104 |
| A | HOH309 |
| A | HOH323 |
| A | HOH421 |
| B | SER128 |
| B | MET130 |
| A | GLY27 |
| A | SER28 |
| A | ILE29 |
| A | ARG30 |
| A | GLY31 |
| A | HIS56 |
| A | VAL57 |
| A | GLU67 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue N6P B 201 |
| Chain | Residue |
| A | SER128 |
| A | MET130 |
| B | CYS26 |
| B | GLY27 |
| B | SER28 |
| B | ILE29 |
| B | ARG30 |
| B | GLY31 |
| B | ILE76 |
| B | ASP80 |
| B | SER98 |
| B | GLY100 |
| B | GLU104 |
| B | HOH317 |
| B | HOH336 |
| B | HOH348 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 202 |
| Chain | Residue |
| B | ASP161 |
| B | PRO162 |
| B | GLU164 |
| B | HOH349 |
| B | HOH362 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25108359","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4P5E","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"PubMed","id":"25108359","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4P5E","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
