4P42
Extended-Synaptotagmin 2, SMP - C2A - C2B Domains
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006869 | biological_process | lipid transport |
| A | 0008289 | molecular_function | lipid binding |
| A | 0061817 | biological_process | endoplasmic reticulum-plasma membrane tethering |
| B | 0006869 | biological_process | lipid transport |
| B | 0008289 | molecular_function | lipid binding |
| B | 0061817 | biological_process | endoplasmic reticulum-plasma membrane tethering |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue EGC A 701 |
| Chain | Residue |
| A | ILE291 |
| A | LEU331 |
| A | PRO334 |
| A | ASN335 |
| A | ARG336 |
| A | ILE337 |
| B | GLU249 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue PEE A 702 |
| Chain | Residue |
| A | VAL214 |
| A | LEU219 |
| A | PHE244 |
| A | ILE326 |
| A | ILE327 |
| A | TYR330 |
| A | LEU331 |
| A | HOH811 |
| A | PHE189 |
| A | ILE193 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EGC B 701 |
| Chain | Residue |
| B | TYR330 |
| B | LEU331 |
| B | PRO334 |
| B | ASN335 |
| B | ARG336 |
| B | ILE337 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue PEE B 702 |
| Chain | Residue |
| B | TRP178 |
| B | ILE193 |
| B | VAL197 |
| B | ALA200 |
| B | LEU219 |
| B | PHE244 |
| B | ILE266 |
| B | LEU318 |
| B | ILE326 |
| B | ILE327 |
| B | TYR330 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 179 |
| Details | Domain: {"description":"SMP-LTD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01194","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24847877","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 120 |
| Details | Domain: {"description":"C2 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00041","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24373768","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
