Functional Information from GO Data
| Chain | GOid | namespace | contents |
| P | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN H 301 |
| Chain | Residue |
| H | ASP213 |
| H | ASP213 |
| H | HOH406 |
| H | HOH406 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN H 302 |
| Chain | Residue |
| H | ASP62 |
| H | IMD315 |
| H | HOH402 |
| H | HOH403 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN H 303 |
| Chain | Residue |
| L | ASP172 |
| L | HOH405 |
| L | HOH407 |
| H | HIS170 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN H 304 |
| Chain | Residue |
| H | IMD314 |
| H | CL316 |
| H | CL317 |
| H | HOH401 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN H 305 |
| Chain | Residue |
| H | CL318 |
| H | CL319 |
| H | HOH405 |
| H | HOH518 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN H 306 |
| Chain | Residue |
| H | GLU1 |
| H | ASP179 |
| H | HOH407 |
| H | HOH444 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ZN H 307 |
| Chain | Residue |
| L | ARG101 |
| L | HOH474 |
| L | HOH475 |
| L | HOH476 |
| P | ASP1 |
| P | PHE4 |
| P | HOH102 |
| P | HOH105 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN H 308 |
| Chain | Residue |
| H | LYS65 |
| H | IMD315 |
| H | IMD315 |
| H | CL320 |
| H | CL320 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN H 309 |
| Chain | Residue |
| H | HOH416 |
| H | HOH478 |
| P | PHE4 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN H 310 |
| Chain | Residue |
| H | THR113 |
| H | HOH408 |
| H | HOH409 |
| H | HOH410 |
| H | HOH463 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN H 311 |
| Chain | Residue |
| H | LYS214 |
| H | HOH452 |
| H | HOH502 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN H 312 |
| Chain | Residue |
| H | ARG44 |
| H | GLU46 |
| H | HOH414 |
| H | HOH474 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN H 313 |
| Chain | Residue |
| H | HOH411 |
| H | HOH412 |
| H | HOH517 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE IMD H 314 |
| Chain | Residue |
| H | THR200 |
| H | SER209 |
| H | LYS211 |
| H | LYS215 |
| H | ZN304 |
| H | CL316 |
| H | CL317 |
| site_id | BC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE IMD H 315 |
| Chain | Residue |
| H | TYR60 |
| H | ASP62 |
| H | ZN302 |
| H | ZN308 |
| H | ZN308 |
| H | CL320 |
| H | HOH403 |
| L | PHE99 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL H 316 |
| Chain | Residue |
| H | PRO206 |
| H | ZN304 |
| H | IMD314 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL H 317 |
| Chain | Residue |
| H | ZN304 |
| H | IMD314 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL H 318 |
| Chain | Residue |
| H | ASN161 |
| H | SER162 |
| H | ASN202 |
| H | ZN305 |
| H | CL319 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL H 319 |
| Chain | Residue |
| H | LYS211 |
| H | ASP213 |
| H | ZN305 |
| H | CL318 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CL H 320 |
| Chain | Residue |
| H | TYR59 |
| H | TYR60 |
| H | LYS65 |
| H | LYS65 |
| H | ZN308 |
| H | ZN308 |
| H | IMD315 |
| site_id | CC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN L 301 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN L 302 |
| Chain | Residue |
| L | HIS194 |
| L | CL319 |
| L | CL320 |
| L | HOH524 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN L 303 |
| Chain | Residue |
| L | HOH408 |
| L | HOH408 |
| L | ASP115 |
| L | ASP115 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN L 304 |
| Chain | Residue |
| L | HIS203 |
| L | CL316 |
| L | CL317 |
| L | HOH406 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN L 305 |
| Chain | Residue |
| L | IMD315 |
| L | HOH401 |
| L | HOH402 |
| L | HOH403 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN L 306 |
| Chain | Residue |
| L | ASP170 |
| L | CL318 |
| L | HOH409 |
| L | HOH410 |
| site_id | CC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ZN L 307 |
| site_id | DC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN L 308 |
| Chain | Residue |
| L | LYS154 |
| L | GLU200 |
| L | HOH502 |
| L | HOH523 |
| site_id | DC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN L 309 |
| Chain | Residue |
| L | GLU84 |
| L | HOH436 |
| site_id | DC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN L 310 |
| Chain | Residue |
| L | HOH430 |
| L | HOH473 |
| L | HOH522 |
| site_id | DC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN L 311 |
| Chain | Residue |
| L | GLY157 |
| L | SER196 |
| L | CL321 |
| L | HOH497 |
| L | HOH521 |
| site_id | DC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ZN L 312 |
| site_id | DC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN L 313 |
| Chain | Residue |
| L | ASP31 |
| L | HOH411 |
| P | ARG5 |
| site_id | DC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN L 314 |
| Chain | Residue |
| H | HIS170 |
| L | ASN143 |
| L | ASP172 |
| L | HOH404 |
| L | HOH407 |
| site_id | DC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IMD L 315 |
| Chain | Residue |
| L | LEU9 |
| L | GLY105 |
| L | GLY106 |
| L | ZN305 |
| site_id | DC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL L 316 |
| Chain | Residue |
| L | ALA116 |
| L | ALA117 |
| L | HIS203 |
| L | ZN304 |
| L | CL317 |
| site_id | EC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL L 317 |
| Chain | Residue |
| L | HIS203 |
| L | ZN304 |
| L | CL316 |
| site_id | EC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL L 318 |
| Chain | Residue |
| L | ASP170 |
| L | ZN306 |
| site_id | EC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL L 319 |
| Chain | Residue |
| L | HIS194 |
| L | ZN302 |
| L | CL320 |
| site_id | EC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL L 320 |
| Chain | Residue |
| L | HIS194 |
| L | ZN302 |
| L | CL319 |
| L | HOH500 |
| site_id | EC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL L 321 |
| Chain | Residue |
| L | ASP156 |
| L | GLY157 |
| L | SER196 |
| L | THR198 |
| L | ZN311 |
| site_id | EC6 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR CHAIN P OF AMYLOID BETA A4 PROTEIN |
| Chain | Residue |
| H | MET34 |
| H | SER35 |
| H | SER50 |
| H | ILE51 |
| H | ARG52 |
| H | TYR59 |
| H | TYR99 |
| H | SER105 |
| H | SER106 |
| H | ZN307 |
| H | ZN309 |
| H | HOH478 |
| L | ASP31 |
| L | TYR37 |
| L | TRP94 |
| L | GLY96 |
| L | THR97 |
| L | HIS98 |
| L | ARG101 |
| L | ZN313 |
| L | HOH413 |
| L | HOH474 |
| L | HOH475 |
| L | HOH476 |
| P | HOH101 |
| P | HOH102 |
| P | HOH103 |
| P | HOH104 |
| P | HOH105 |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH |
| Chain | Residue | Details |
| L | TYR197-HIS203 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by caspase-6; when associated with variant 670-N-L-671"} |
