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4OG6

Human menin with bound inhibitor MIV-4

Functional Information from GO Data
ChainGOidnamespacecontents
A0005634cellular_componentnucleus
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 601
ChainResidue
ATYR133
APHE134
AARG137
AARG332

site_idAC2
Number of Residues16
DetailsBINDING SITE FOR RESIDUE 2S9 A 602
ChainResidue
APHE238
AALA242
AMET278
ATYR319
AMET322
ATYR323
ATRP341
AGLU363
AHOH1032
AHOH1048
AHOH1078
ASER155
ASER178
AASP180
AHIS181
AALA182

site_idAC3
Number of Residues7
DetailsBINDING SITE FOR RESIDUE PG4 A 603
ChainResidue
ALEU75
ATHR76
APHE365
AHOH735
AHOH776
AHOH856
AHOH875

site_idAC4
Number of Residues3
DetailsBINDING SITE FOR RESIDUE PEG A 604
ChainResidue
ATRP126
ALYS135
ATRP198

site_idAC5
Number of Residues3
DetailsBINDING SITE FOR RESIDUE PEG A 605
ChainResidue
ATYR268
AASP269
AGLY271

site_idAC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE DMS A 606
ChainResidue
APRO12
AARG14
AHOH977
AHOH1100

site_idAC7
Number of Residues6
DetailsBINDING SITE FOR RESIDUE DMS A 607
ChainResidue
AVAL185
AGLY190
AGLU191
ATYR227
AARG229
ASER583

site_idAC8
Number of Residues4
DetailsBINDING SITE FOR RESIDUE DMS A 608
ChainResidue
AARG332
AVAL334
AARG335
AALA403

site_idAC9
Number of Residues4
DetailsBINDING SITE FOR RESIDUE DMS A 609
ChainResidue
APHE47
AGLY386
AGLN400
AHOH794

site_idBC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE PEG A 610
ChainResidue
AHIS46
AASN51
ALEU382
AHOH1144
AHOH1161
AHOH1163

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails

226707

PDB entries from 2024-10-30

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