4O5I

Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/361/2011 (H3N2) influenza hemagglutinin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0019031	cellular_component	viral envelope
A	0019064	biological_process	fusion of virus membrane with host plasma membrane
A	0046789	molecular_function	host cell surface receptor binding
B	0019031	cellular_component	viral envelope
B	0019064	biological_process	fusion of virus membrane with host plasma membrane
B	0046789	molecular_function	host cell surface receptor binding
C	0019031	cellular_component	viral envelope
C	0019064	biological_process	fusion of virus membrane with host plasma membrane
C	0046789	molecular_function	host cell surface receptor binding
D	0019031	cellular_component	viral envelope
D	0019064	biological_process	fusion of virus membrane with host plasma membrane
D	0046789	molecular_function	host cell surface receptor binding
E	0019031	cellular_component	viral envelope
E	0019064	biological_process	fusion of virus membrane with host plasma membrane
E	0046789	molecular_function	host cell surface receptor binding
F	0019031	cellular_component	viral envelope
F	0019064	biological_process	fusion of virus membrane with host plasma membrane
F	0046789	molecular_function	host cell surface receptor binding
G	0019031	cellular_component	viral envelope
G	0019064	biological_process	fusion of virus membrane with host plasma membrane
G	0046789	molecular_function	host cell surface receptor binding
H	0019031	cellular_component	viral envelope
H	0019064	biological_process	fusion of virus membrane with host plasma membrane
H	0046789	molecular_function	host cell surface receptor binding
I	0019031	cellular_component	viral envelope
I	0019064	biological_process	fusion of virus membrane with host plasma membrane
I	0046789	molecular_function	host cell surface receptor binding
J	0019031	cellular_component	viral envelope
J	0019064	biological_process	fusion of virus membrane with host plasma membrane
J	0046789	molecular_function	host cell surface receptor binding
K	0019031	cellular_component	viral envelope
K	0019064	biological_process	fusion of virus membrane with host plasma membrane
K	0046789	molecular_function	host cell surface receptor binding
L	0019031	cellular_component	viral envelope
L	0019064	biological_process	fusion of virus membrane with host plasma membrane
L	0046789	molecular_function	host cell surface receptor binding
N	0002250	biological_process	adaptive immune response
N	0002376	biological_process	immune system process
N	0003823	molecular_function	antigen binding
N	0005576	cellular_component	extracellular region
N	0005615	cellular_component	extracellular space
N	0005886	cellular_component	plasma membrane
N	0016064	biological_process	immunoglobulin mediated immune response
N	0019814	cellular_component	immunoglobulin complex
N	0070062	cellular_component	extracellular exosome
N	0071735	cellular_component	IgG immunoglobulin complex
N	0072562	cellular_component	blood microparticle
P	0002250	biological_process	adaptive immune response
P	0002376	biological_process	immune system process
P	0003823	molecular_function	antigen binding
P	0005576	cellular_component	extracellular region
P	0005615	cellular_component	extracellular space
P	0005886	cellular_component	plasma membrane
P	0016064	biological_process	immunoglobulin mediated immune response
P	0019814	cellular_component	immunoglobulin complex
P	0070062	cellular_component	extracellular exosome
P	0071735	cellular_component	IgG immunoglobulin complex
P	0072562	cellular_component	blood microparticle
R	0002250	biological_process	adaptive immune response
R	0002376	biological_process	immune system process
R	0003823	molecular_function	antigen binding
R	0005576	cellular_component	extracellular region
R	0005615	cellular_component	extracellular space
R	0005886	cellular_component	plasma membrane
R	0016064	biological_process	immunoglobulin mediated immune response
R	0019814	cellular_component	immunoglobulin complex
R	0070062	cellular_component	extracellular exosome
R	0071735	cellular_component	IgG immunoglobulin complex
R	0072562	cellular_component	blood microparticle
T	0002250	biological_process	adaptive immune response
T	0002376	biological_process	immune system process
T	0003823	molecular_function	antigen binding
T	0005576	cellular_component	extracellular region
T	0005615	cellular_component	extracellular space
T	0005886	cellular_component	plasma membrane
T	0016064	biological_process	immunoglobulin mediated immune response
T	0019814	cellular_component	immunoglobulin complex
T	0070062	cellular_component	extracellular exosome
T	0071735	cellular_component	IgG immunoglobulin complex
T	0072562	cellular_component	blood microparticle
V	0002250	biological_process	adaptive immune response
V	0002376	biological_process	immune system process
V	0003823	molecular_function	antigen binding
V	0005576	cellular_component	extracellular region
V	0005615	cellular_component	extracellular space
V	0005886	cellular_component	plasma membrane
V	0016064	biological_process	immunoglobulin mediated immune response
V	0019814	cellular_component	immunoglobulin complex
V	0070062	cellular_component	extracellular exosome
V	0071735	cellular_component	IgG immunoglobulin complex
V	0072562	cellular_component	blood microparticle
X	0002250	biological_process	adaptive immune response
X	0002376	biological_process	immune system process
X	0003823	molecular_function	antigen binding
X	0005576	cellular_component	extracellular region
X	0005615	cellular_component	extracellular space
X	0005886	cellular_component	plasma membrane
X	0016064	biological_process	immunoglobulin mediated immune response
X	0019814	cellular_component	immunoglobulin complex
X	0070062	cellular_component	extracellular exosome
X	0071735	cellular_component	IgG immunoglobulin complex
X	0072562	cellular_component	blood microparticle

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
M	TYR194-HIS200
N	TYR191-HIS197

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI5
Number of Residues	564
Details	Domain: {"description":"Ig-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---