Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004540 | molecular_function | RNA nuclease activity |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006397 | biological_process | mRNA processing |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004540 | molecular_function | RNA nuclease activity |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006397 | biological_process | mRNA processing |
| B | 0006468 | biological_process | protein phosphorylation |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004540 | molecular_function | RNA nuclease activity |
| C | 0004672 | molecular_function | protein kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006397 | biological_process | mRNA processing |
| C | 0006468 | biological_process | protein phosphorylation |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004540 | molecular_function | RNA nuclease activity |
| D | 0004672 | molecular_function | protein kinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006397 | biological_process | mRNA processing |
| D | 0006468 | biological_process | protein phosphorylation |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 25L A 1000 |
| Chain | Residue |
| A | GLN32 |
| A | PHE124 |
| A | GLU129 |
| A | TYR133 |
| A | ARG153 |
| A | LYS164 |
| B | ARG307 |
| B | ARG308 |
| B | TYR310 |
| B | ARG353 |
| B | PHE362 |
| A | TRP56 |
| B | SER426 |
| A | TRP58 |
| A | SER63 |
| A | GLN66 |
| A | LYS87 |
| A | ASN89 |
| A | ILE99 |
| A | ASN122 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 25L B 1000 |
| Chain | Residue |
| A | ARG307 |
| A | ARG308 |
| A | TYR310 |
| A | ARG353 |
| A | PHE362 |
| B | TRP56 |
| B | TRP58 |
| B | SER63 |
| B | GLN66 |
| B | LYS87 |
| B | ASN89 |
| B | ASP120 |
| B | ASN122 |
| B | PHE124 |
| B | GLU129 |
| B | TYR133 |
| B | ARG153 |
| B | LYS164 |
| site_id | AC3 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE 25L C 1000 |
| Chain | Residue |
| C | TRP56 |
| C | TRP58 |
| C | SER63 |
| C | GLN66 |
| C | LYS87 |
| C | ASN89 |
| C | ILE99 |
| C | ASP120 |
| C | ASN122 |
| C | PHE124 |
| C | GLU129 |
| C | TYR133 |
| C | ARG153 |
| C | LYS164 |
| D | ARG307 |
| D | ARG308 |
| D | TYR310 |
| D | ARG353 |
| D | PHE362 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 25L D 1000 |
| Chain | Residue |
| C | ARG307 |
| C | ARG308 |
| C | TYR310 |
| C | ARG353 |
| C | PHE362 |
| D | TRP56 |
| D | TRP58 |
| D | SER63 |
| D | GLN66 |
| D | LYS87 |
| D | ASN89 |
| D | ILE99 |
| D | ASN122 |
| D | PHE124 |
| D | GLU129 |
| D | TYR133 |
| D | ARG153 |
| D | LYS164 |
Functional Information from PROSITE/UniProt
| site_id | PS00066 |
| Number of Residues | 15 |
| Details | HMG_COA_REDUCTASE_1 Hydroxymethylglutaryl-coenzyme A reductases signature 1. KaEVdARDnMGrNaL |
| Chain | Residue | Details |
| A | LYS190-LEU204 | |
