4NZ0
The EMCV 3Dpol structure at 2.8A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0039694 | biological_process | viral RNA genome replication |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| B | 0006351 | biological_process | DNA-templated transcription |
| B | 0039694 | biological_process | viral RNA genome replication |
| C | 0003723 | molecular_function | RNA binding |
| C | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| C | 0006351 | biological_process | DNA-templated transcription |
| C | 0039694 | biological_process | viral RNA genome replication |
| D | 0003723 | molecular_function | RNA binding |
| D | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| D | 0006351 | biological_process | DNA-templated transcription |
| D | 0039694 | biological_process | viral RNA genome replication |
| E | 0003723 | molecular_function | RNA binding |
| E | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| E | 0006351 | biological_process | DNA-templated transcription |
| E | 0039694 | biological_process | viral RNA genome replication |
| F | 0003723 | molecular_function | RNA binding |
| F | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| F | 0006351 | biological_process | DNA-templated transcription |
| F | 0039694 | biological_process | viral RNA genome replication |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL D 501 |
| Chain | Residue |
| D | CYS212 |
| D | TYR331 |
| D | HOH604 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 502 |
| Chain | Residue |
| D | THR447 |
| D | SER450 |
| F | ALA252 |
| F | LYS267 |
| F | GLU271 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL D 503 |
| Chain | Residue |
| D | THR18 |
| D | PRO35 |
| D | ALA36 |
| D | LEU38 |
| D | SER39 |
| D | ASP42 |
| D | ARG44 |
| F | PHE459 |
| F | TRP460 |
| D | ARG16 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 504 |
| Chain | Residue |
| D | GLY410 |
| D | LEU412 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL E 501 |
| Chain | Residue |
| A | ARG439 |
| E | TYR318 |
| E | GLN342 |
| E | ASN344 |
| E | ARG347 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL E 503 |
| Chain | Residue |
| A | PRO43 |
| A | ASP46 |
| E | TYR407 |
| E | PRO409 |
| E | GLY410 |
| E | THR411 |
| E | LEU412 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL F 501 |
| Chain | Residue |
| F | ARG284 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL F 502 |
| Chain | Residue |
| D | SER413 |
| D | LEU416 |
| D | VAL443 |
| F | THR63 |
| F | LEU64 |
| F | PRO65 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 708 |
| Details | Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Active site: {"description":"For RdRp activity","evidences":[{"source":"PubMed","id":"24600002","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
