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4NGD

Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 12-mer siRNA having 5'-p and UU-3' ends (1.95 Angstrom resolution)

Functional Information from GO Data
ChainGOidnamespacecontents
A0003723molecular_functionRNA binding
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A 1101
ChainResidue
AARG778
AARG780
AARG811
AHIS982
AARG993

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE SO4 A 1102
ChainResidue
ATYR926
APHE929
APHE929
APEG1103
APEG1103
AILE899
AILE899
AARG925
ATYR926

site_idAC3
Number of Residues10
DetailsBINDING SITE FOR RESIDUE PEG A 1103
ChainResidue
ATYR926
ATYR926
AARG927
AASN928
APHE929
ATYR966
ASO41102
ASO41102
APEG1104
AHOH1355

site_idAC4
Number of Residues9
DetailsBINDING SITE FOR RESIDUE PEG A 1104
ChainResidue
AARG927
AASN928
ATYR966
ATYR966
AASN967
APEG1103
BG1
BC10
BU11

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648
ChainResidueDetails
ASER1006

226707

PDB entries from 2024-10-30

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