4NEE

crystal structure of AP-2 alpha/simga2 complex bound to HIV-1 Nef

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006886	biological_process	intracellular protein transport
A	0016192	biological_process	vesicle-mediated transport
A	0030117	cellular_component	membrane coat
B	0006886	biological_process	intracellular protein transport
B	0016192	biological_process	vesicle-mediated transport
B	0030117	cellular_component	membrane coat
C	0005525	molecular_function	GTP binding
D	0005886	cellular_component	plasma membrane
D	0005905	cellular_component	clathrin-coated pit
D	0006886	biological_process	intracellular protein transport
D	0006897	biological_process	endocytosis
D	0008021	cellular_component	synaptic vesicle
D	0008150	biological_process	biological_process
D	0015031	biological_process	protein transport
D	0016020	cellular_component	membrane
D	0016192	biological_process	vesicle-mediated transport
D	0030117	cellular_component	membrane coat
D	0030122	cellular_component	AP-2 adaptor complex
D	0035615	molecular_function	clathrin adaptor activity
D	0045202	cellular_component	synapse
D	0048488	biological_process	synaptic vesicle endocytosis
D	0072583	biological_process	clathrin-dependent endocytosis
D	0098794	cellular_component	postsynapse
D	0098884	biological_process	postsynaptic neurotransmitter receptor internalization
D	0098894	cellular_component	extrinsic component of presynaptic endocytic zone membrane
D	0098978	cellular_component	glutamatergic synapse
E	0005525	molecular_function	GTP binding
F	0005886	cellular_component	plasma membrane
F	0005905	cellular_component	clathrin-coated pit
F	0006886	biological_process	intracellular protein transport
F	0006897	biological_process	endocytosis
F	0008021	cellular_component	synaptic vesicle
F	0008150	biological_process	biological_process
F	0015031	biological_process	protein transport
F	0016020	cellular_component	membrane
F	0016192	biological_process	vesicle-mediated transport
F	0030117	cellular_component	membrane coat
F	0030122	cellular_component	AP-2 adaptor complex
F	0035615	molecular_function	clathrin adaptor activity
F	0045202	cellular_component	synapse
F	0048488	biological_process	synaptic vesicle endocytosis
F	0072583	biological_process	clathrin-dependent endocytosis
F	0098794	cellular_component	postsynapse
F	0098884	biological_process	postsynaptic neurotransmitter receptor internalization
F	0098894	cellular_component	extrinsic component of presynaptic endocytic zone membrane
F	0098978	cellular_component	glutamatergic synapse
G	0006886	biological_process	intracellular protein transport
G	0016192	biological_process	vesicle-mediated transport
G	0030117	cellular_component	membrane coat
H	0005525	molecular_function	GTP binding
I	0005886	cellular_component	plasma membrane
I	0005905	cellular_component	clathrin-coated pit
I	0006886	biological_process	intracellular protein transport
I	0006897	biological_process	endocytosis
I	0008021	cellular_component	synaptic vesicle
I	0008150	biological_process	biological_process
I	0015031	biological_process	protein transport
I	0016020	cellular_component	membrane
I	0016192	biological_process	vesicle-mediated transport
I	0030117	cellular_component	membrane coat
I	0030122	cellular_component	AP-2 adaptor complex
I	0035615	molecular_function	clathrin adaptor activity
I	0045202	cellular_component	synapse
I	0048488	biological_process	synaptic vesicle endocytosis
I	0072583	biological_process	clathrin-dependent endocytosis
I	0098794	cellular_component	postsynapse
I	0098884	biological_process	postsynaptic neurotransmitter receptor internalization
I	0098894	cellular_component	extrinsic component of presynaptic endocytic zone membrane
I	0098978	cellular_component	glutamatergic synapse
J	0006886	biological_process	intracellular protein transport
J	0016192	biological_process	vesicle-mediated transport
J	0030117	cellular_component	membrane coat
K	0005525	molecular_function	GTP binding
L	0005886	cellular_component	plasma membrane
L	0005905	cellular_component	clathrin-coated pit
L	0006886	biological_process	intracellular protein transport
L	0006897	biological_process	endocytosis
L	0008021	cellular_component	synaptic vesicle
L	0008150	biological_process	biological_process
L	0015031	biological_process	protein transport
L	0016020	cellular_component	membrane
L	0016192	biological_process	vesicle-mediated transport
L	0030117	cellular_component	membrane coat
L	0030122	cellular_component	AP-2 adaptor complex
L	0035615	molecular_function	clathrin adaptor activity
L	0045202	cellular_component	synapse
L	0048488	biological_process	synaptic vesicle endocytosis
L	0072583	biological_process	clathrin-dependent endocytosis
L	0098794	cellular_component	postsynapse
L	0098884	biological_process	postsynaptic neurotransmitter receptor internalization
L	0098894	cellular_component	extrinsic component of presynaptic endocytic zone membrane
L	0098978	cellular_component	glutamatergic synapse

Functional Information from PROSITE/UniProt

site_id	PS00989
Number of Residues	11
Details	CLAT_ADAPTOR_S Clathrin adaptor complexes small chain signature. IIYRryagLYF

Chain	Residue	Details
D	ILE57-PHE67

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P53680","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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