4MRT
Structure of the Phosphopantetheine Transferase Sfp in Complex with Coenzyme A and a Peptidyl Carrier Protein
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0008897 | molecular_function | holo-[acyl-carrier-protein] synthase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0017000 | biological_process | antibiotic biosynthetic process |
| A | 0019878 | biological_process | lysine biosynthetic process via aminoadipic acid |
| A | 0046872 | molecular_function | metal ion binding |
| A | 1900192 | biological_process | positive regulation of single-species biofilm formation |
| C | 0031177 | molecular_function | phosphopantetheine binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 301 |
| Chain | Residue |
| A | ASP107 |
| A | GLU151 |
| A | COA302 |
| A | HOH468 |
| A | HOH469 |
| site_id | AC2 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE COA A 302 |
| Chain | Residue |
| A | LYS75 |
| A | PRO76 |
| A | ASN87 |
| A | ILE88 |
| A | SER89 |
| A | HIS90 |
| A | ASP107 |
| A | GLU151 |
| A | LYS155 |
| A | GLY158 |
| A | LYS159 |
| A | GLY160 |
| A | LEU161 |
| A | SER162 |
| A | MG301 |
| A | GOL303 |
| A | MG304 |
| A | HOH402 |
| A | HOH403 |
| A | HOH414 |
| A | HOH441 |
| A | HOH443 |
| A | HOH444 |
| A | HOH468 |
| A | HOH469 |
| A | HOH527 |
| A | HOH529 |
| A | HOH530 |
| A | HOH531 |
| C | HIS44 |
| C | ALA45 |
| C | PHE69 |
| A | LYS31 |
| A | THR44 |
| A | TYR73 |
| A | GLY74 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 303 |
| Chain | Residue |
| A | LYS28 |
| A | ASP48 |
| A | PHE68 |
| A | ILE88 |
| A | COA302 |
| A | HOH444 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 304 |
| Chain | Residue |
| A | HIS90 |
| A | COA302 |
| A | HOH527 |
| A | HOH528 |
| A | HOH529 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 305 |
| Chain | Residue |
| A | LYS75 |
| A | HIS85 |
| A | HOH440 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"O-(pantetheine 4'-phosphoryl)serine","evidences":[{"source":"PROSITE-ProRule","id":"PRU00258","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10801488","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 31 |
| Details | Region: {"description":"Peptidyl carrier protein binding","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {} |
| Chain | Residue | Details |
