Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | HIS37 |
| A | ARG37 |
| A | HOH1171 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1002 |
| Chain | Residue |
| A | HOH1259 |
| A | HOH1265 |
| A | THR39 |
| A | TYR40 |
| A | HOH1141 |
| A | HOH1144 |
| A | HOH1200 |
| A | HOH1222 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 1003 |
| Chain | Residue |
| A | VAL41 |
| A | HIS57 |
| A | GLN192 |
| A | GLY193 |
| A | SER195 |
| A | HOH1258 |
| C | TYR6 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 1004 |
| Chain | Residue |
| A | ARG239 |
| A | THR242 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1005 |
| Chain | Residue |
| A | HIS100 |
| A | ASN101 |
| A | THR177 |
| A | LYS179 |
| A | MET180 |
| A | HOH1227 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 1006 |
| Chain | Residue |
| A | HIS165 |
| A | ARG166 |
| A | HOH1317 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 301 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 302 |
| Chain | Residue |
| B | THR39 |
| B | TYR40 |
| B | TYR151 |
| B | ACT306 |
| B | HOH470 |
| B | HOH525 |
| B | HOH527 |
| B | HOH528 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT B 303 |
| Chain | Residue |
| B | VAL41 |
| B | HIS57 |
| B | GLN192 |
| B | GLY193 |
| B | SER195 |
| B | HOH401 |
| D | TYR6 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT B 304 |
| Chain | Residue |
| B | TYR67 |
| B | ARG70 |
| B | HOH454 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 305 |
| Chain | Residue |
| B | HIS100 |
| B | ASN101 |
| B | THR177 |
| B | LYS179 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 306 |
| Chain | Residue |
| B | LEU73 |
| B | ASN74 |
| B | TYR151 |
| B | SO4302 |
| site_id | BC4 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR BICYCLIC PEPTIDE UK903 |
| Chain | Residue |
| A | HIS57 |
| A | ASP60 |
| A | HIS99 |
| A | LYS143 |
| A | SER146 |
| A | THR147 |
| A | ASP148 |
| A | SER190 |
| A | CYS191 |
| A | GLN192 |
| A | SER195 |
| A | VAL213 |
| A | SER214 |
| A | TRP215 |
| A | GLY216 |
| A | ARG217 |
| A | GLY218 |
| A | CYS220 |
| A | GLY226 |
| A | ACT1003 |
| A | HOH1106 |
| A | HOH1108 |
| A | HOH1123 |
| A | HOH1159 |
| A | HOH1160 |
| C | HOH201 |
| C | HOH202 |
| C | HOH203 |
| C | HOH204 |
| C | HOH206 |
| C | HOH207 |
| C | HOH212 |
| C | HOH214 |
| C | HOH215 |
| C | HOH216 |
| C | HOH217 |
| site_id | BC5 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR BICYCLIC PEPTIDE UK903 |
| Chain | Residue |
| B | ASP148 |
| B | SER190 |
| B | CYS191 |
| B | GLN192 |
| B | SER195 |
| B | VAL213 |
| B | TRP215 |
| B | GLY216 |
| B | ARG217 |
| B | GLY218 |
| B | CYS220 |
| B | GLY226 |
| B | ACT303 |
| B | HOH413 |
| B | HOH427 |
| B | HOH446 |
| D | HOH201 |
| D | HOH202 |
| D | HOH203 |
| D | HOH204 |
| D | HOH205 |
| D | HOH206 |
| D | HOH207 |
| D | HOH209 |
| D | HOH210 |
| D | HOH213 |
| D | HOH221 |
| D | HOH222 |
| B | HIS57 |
| B | ASP60 |
| B | HIS99 |
| B | LYS143 |
| B | SER146 |
| B | THR147 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. ISATHC |
| Chain | Residue | Details |
| A | ILE53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Charge relay system"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"9151681","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000026"} |
