Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | CYS190 |
| A | CYS193 |
| A | CYS225 |
| A | CYS227 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 402 |
| Chain | Residue |
| A | SER112 |
| A | SER115 |
| A | SER116 |
| A | TYR274 |
| A | HOH702 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE NHE A 403 |
| Chain | Residue |
| A | LYS106 |
| A | TRP107 |
| A | ASP287 |
| A | GLY288 |
| A | ALA289 |
| A | HIS290 |
| A | THR313 |
| A | ILE315 |
| A | HOH520 |
| A | HOH561 |
| A | HOH742 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NHE A 404 |
| Chain | Residue |
| A | GLN123 |
| A | LEU124 |
| A | GLU125 |
| A | ARG141 |
| A | HOH703 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 405 |
| Chain | Residue |
| A | HIS18 |
| A | GLN20 |
| A | ASP62 |
| A | THR64 |
| A | LEU65 |
| A | HOH639 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 406 |
| Chain | Residue |
| A | TYR252 |
| A | LYS253 |
| A | LEU254 |
| A | GLN255 |
| A | THR258 |
| A | TYR306 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 101 |
| Chain | Residue |
| B | GLU24 |
| B | ASN25 |
| B | ALA28 |
Functional Information from PROSITE/UniProt
| site_id | PS00299 |
| Number of Residues | 26 |
| Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
| Chain | Residue | Details |
| B | LYS27-ASP52 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Interacts with activating enzyme |
| Chain | Residue | Details |
| B | ARG54 | |
| B | ARG72 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Essential for function |
| Chain | Residue | Details |
| B | HIS68 | |
| Chain | Residue | Details |
| B | SER65 | |
| A | ASP287 | |
| Chain | Residue | Details |
| B | GLY76 | |
| A | CYS193 | |
| A | CYS225 | |
| A | CYS227 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 7 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P62979 |
| Chain | Residue | Details |
| B | LYS6 | |
| B | LYS11 | |
| B | LYS27 | |
| B | LYS29 | |
| B | LYS33 | |
| B | LYS48 | |
| B | LYS63 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) |
| Chain | Residue | Details |
| B | GLY76 | |
