4LWU

The 1.14A Crystal Structure of Humanized Xenopus MDM2 with RO5499252

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0043066	biological_process	negative regulation of apoptotic process
A	0051726	biological_process	regulation of cell cycle

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE 20U A 201

Chain	Residue
A	LEU50
A	ILE95
A	TYR96
A	SO4202
A	HOH316
A	HOH375
A	HOH419
A	ILE57
A	HIS69
A	PHE82
A	GLN85
A	PHE87
A	VAL89
A	LYS90
A	HIS92

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 A 202

Chain	Residue
A	TYR63
A	GLU65
A	LYS66
A	HIS69
A	20U201
A	HOH304
A	HOH397
A	HOH400
A	HOH419

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