4LCF

Crystal structure of the Pseudomonas aeruginosa LPXC/LPC-014 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005737	cellular_component	cytoplasm
A	0006629	biological_process	lipid metabolic process
A	0009245	biological_process	lipid A biosynthetic process
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
A	0103117	molecular_function	UDP-3-O-acyl-N-acetylglucosamine deacetylase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 301

Chain	Residue
A	HIS162
A	GLU219
A	ASP277
A	ASP279

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN A 302

Chain	Residue
A	ARG166

---

site_id	AC3
Number of Residues	20
Details	BINDING SITE FOR RESIDUE 1WL A 303

Chain	Residue
A	GLN115
A	SER116
A	THR190
A	PHE191
A	ILE197
A	GLY209
A	SER210
A	VAL216
A	HIS237
A	ASP241
A	HIS264
A	NO3309
A	ZN311
A	HOH622
A	HOH651
A	HOH657
A	MET62
A	GLU77
A	HIS78
A	PHE112

---

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE NO3 A 304

Chain	Residue
A	ILE158
A	ARG168
A	THR169
A	GLN170
A	ASP232
A	GLU233
A	PHE234
A	VAL235
A	HOH465

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NO3 A 305

Chain	Residue
A	ILE10
A	ARG12
A	ARG143
A	ARG258
A	PHE260

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NO3 A 306

Chain	Residue
A	ILE158
A	ASP159
A	PHE160
A	LYS261
A	HOH621

---

site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE NO3 A 307

Chain	Residue
A	ARG189
A	SER202
A	GLN203
A	ASN204
A	ARG229
A	HOH422
A	HOH467
A	HOH520
A	HOH559

---

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE NO3 A 308

Chain	Residue
A	GLU139
A	LYS142
A	LYS261
A	SER262
A	GLY263
A	ALA265
A	LEU266
A	HOH586

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NO3 A 309

Chain	Residue
A	THR61
A	LYS238
A	GLY263
A	HIS264
A	1WL303
A	HOH452
A	HOH478

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NO3 A 310

Chain	Residue
A	ALA31
A	PRO32
A	GLN122
A	HOH441

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 311

Chain	Residue
A	HIS78
A	HIS237
A	ASP241
A	1WL303

---

site_id	BC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE NO3 A 312

Chain	Residue
A	ARG12
A	THR14
A	ARG133
A	GLU134
A	PRO148
A	HOH402
A	HOH491
A	HOH631

---

site_id	BC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE NO3 A 313

Chain	Residue
A	TYR25
A	SER96
A	PRO148
A	PHE149
A	ASP150
A	HOH412
A	HOH433
A	HOH489

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NO3 A 314

Chain	Residue
A	TYR230
A	GLU231
A	ASP232
A	LYS236

---

site_id	BC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE NO3 A 315

Chain	Residue
A	ILE294
A	SER295
A	HOH454
A	HOH563
A	HOH594
A	HOH632
A	PHE176
A	SER177
A	PRO293

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00388","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00388","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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