4L8F
Crystal structure of gamma-glutamyl hydrolase (C108A) complex with MTX
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008242 | molecular_function | omega peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0008242 | molecular_function | omega peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0008242 | molecular_function | omega peptidase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0008242 | molecular_function | omega peptidase activity |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE MTX D 301 |
| Chain | Residue |
| D | PHE20 |
| D | GLN170 |
| D | TRP171 |
| D | HIS218 |
| D | HOH430 |
| D | HOH637 |
| D | GLY71 |
| D | GLY72 |
| D | GLY73 |
| D | ALA108 |
| D | LEU109 |
| D | GLU112 |
| D | SER168 |
| D | HIS169 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE MTX B 301 |
| Chain | Residue |
| B | PHE20 |
| B | GLY71 |
| B | GLY72 |
| B | GLY73 |
| B | ALA108 |
| B | LEU109 |
| B | GLU112 |
| B | SER168 |
| B | HIS169 |
| B | GLN170 |
| B | TRP171 |
| B | HIS218 |
| B | HOH407 |
| B | HOH430 |
| B | HOH600 |
