4KQ3

Crystal structure of Anti-IL-17A antibody CNTO3186

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL L 301

Chain	Residue
H	HIS168
H	HOH1113
L	THR163
L	GLU164
L	ASP166
L	THR171
L	HOH402
L	HOH472

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL L 302

Chain	Residue
H	PRO171
H	LEU182
H	SER183
L	SER161
L	SER175
L	SER176
L	THR177
L	HOH417
H	PHE170

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site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL L 303

Chain	Residue
L	GLN37
L	LYS45
L	PRO59
L	ARG61
L	GLU81
L	ASP82
L	HOH517

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site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MES H 1001

Chain	Residue
H	VAL93
H	GLN109
H	GLY110
H	LYS205
H	HOH1145
H	HOH1208
H	HOH1212

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site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO H 1002

Chain	Residue
H	ASN159
H	GLN196
H	THR197
H	HOH1137
H	HOH1139
L	ARG141
L	GLU160
L	VAL162

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR198-HIS204
L	TYR191-HIS197

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