Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| A | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| A | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
| B | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| B | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 1QP A 601 |
| Chain | Residue |
| A | GLN91 |
| B | GLU138 |
| B | THR139 |
| B | PRO140 |
| A | GLN161 |
| A | THR165 |
| A | GLU169 |
| A | ILE180 |
| A | TYR181 |
| A | GLN182 |
| A | DMS604 |
| A | HOH734 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS A 602 |
| Chain | Residue |
| A | TYR427 |
| A | GLN428 |
| A | LEU525 |
| A | LYS528 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS A 603 |
| Chain | Residue |
| A | ARG277 |
| A | GLN278 |
| A | LYS281 |
| A | ARG356 |
| A | LYS512 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS A 604 |
| Chain | Residue |
| A | VAL90 |
| A | GLN91 |
| A | TYR181 |
| A | 1QP601 |
| B | ASN137 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE DMS A 605 |
| Chain | Residue |
| A | ASN363 |
| A | TRP401 |
| A | LYS424 |
| A | LEU425 |
| A | TRP426 |
| A | TYR427 |
| A | GLN509 |
| A | HOH729 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMS A 606 |
| Chain | Residue |
| A | GLY333 |
| A | GLN334 |
| A | LYS512 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE T27 A 607 |
| Chain | Residue |
| A | LEU100 |
| A | LYS101 |
| A | TYR181 |
| A | TYR188 |
| A | PRO225 |
| A | PHE227 |
| A | TRP229 |
| A | LEU234 |
| A | HIS235 |
| A | PRO236 |
| A | TYR318 |
| A | HOH923 |
| B | GLU138 |
| B | HOH628 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS B 501 |
| Chain | Residue |
| A | HOH984 |
| B | PRO55 |
| B | TYR56 |
| B | LYS126 |
| B | HOH653 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DMS B 502 |
| Chain | Residue |
| A | THR376 |
| B | THR27 |
| B | THR388 |
| B | TRP389 |
| B | GLU392 |
| B | HOH792 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS B 503 |
| Chain | Residue |
| B | ILE258 |
| B | TYR259 |
| B | VAL302 |
| B | ASN336 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMS B 504 |
| Chain | Residue |
| A | ILE380 |
| A | VAL381 |
| B | PRO25 |
| B | LEU26 |
| B | PRO133 |
| B | SER134 |
| B | ASN136 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE DMS B 505 |
| Chain | Residue |
| B | TRP24 |
| B | GLU387 |
| B | TRP390 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: |
| Chain | Residue | Details |
| B | ASP110 | |
| B | ASP185 | |
| B | ASP186 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Essential for RT p66/p51 heterodimerization |
| Chain | Residue | Details |
| B | TRP389 | |
| B | TRP402 | |
| A | ASP498 | |
| A | ASP549 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Essential for RT p66/p51 heterodimerization |
| Chain | Residue | Details |
| A | TRP401 | |
| A | TRP414 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by viral protease; partial |
| Chain | Residue | Details |
| A | PHE440 | |
