4IJL
Fragment-based Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 1EK A 201 |
| Chain | Residue |
| A | ARG7 |
| A | HOH349 |
| A | ARG41 |
| A | ALA59 |
| A | THR60 |
| A | ASN85 |
| A | 1EK202 |
| A | HOH306 |
| A | HOH318 |
| A | HOH339 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 1EK A 202 |
| Chain | Residue |
| A | ARG31 |
| A | ARG43 |
| A | SER55 |
| A | MET57 |
| A | VAL93 |
| A | 1EK201 |
| A | HOH341 |
| A | HOH355 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"19413330","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"26474068","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
