4I0C
The structure of the camelid antibody cAbHuL5 in complex with human lysozyme
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003796 | molecular_function | lysozyme activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0006954 | biological_process | inflammatory response |
| A | 0019730 | biological_process | antimicrobial humoral response |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0035578 | cellular_component | azurophil granule lumen |
| A | 0035580 | cellular_component | specific granule lumen |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0050829 | biological_process | defense response to Gram-negative bacterium |
| A | 0050830 | biological_process | defense response to Gram-positive bacterium |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 1904724 | cellular_component | tertiary granule lumen |
| B | 0003796 | molecular_function | lysozyme activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0006954 | biological_process | inflammatory response |
| B | 0019730 | biological_process | antimicrobial humoral response |
| B | 0031640 | biological_process | killing of cells of another organism |
| B | 0035578 | cellular_component | azurophil granule lumen |
| B | 0035580 | cellular_component | specific granule lumen |
| B | 0042742 | biological_process | defense response to bacterium |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0050829 | biological_process | defense response to Gram-negative bacterium |
| B | 0050830 | biological_process | defense response to Gram-positive bacterium |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 1904724 | cellular_component | tertiary granule lumen |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 201 |
| Chain | Residue |
| A | GLY72 |
| B | ASN66 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 202 |
| Chain | Residue |
| A | ARG101 |
| A | ARG101 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 203 |
| Chain | Residue |
| A | ARG21 |
| D | HOH218 |
| D | HOH238 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 204 |
| Chain | Residue |
| A | ALA108 |
| A | HOH390 |
| A | HOH391 |
| A | GLN58 |
| A | ASN60 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 201 |
| Chain | Residue |
| B | LYS33 |
| B | HOH370 |
| C | SER125 |
| C | SER126 |
| C | HOH318 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 202 |
| Chain | Residue |
| B | GLN58 |
| B | ILE59 |
| B | ASN60 |
| B | TRP64 |
| B | ALA108 |
| B | TRP109 |
| B | HOH358 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 201 |
| Chain | Residue |
| C | LYS97 |
| C | SER102 |
| C | SER105 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 202 |
| Chain | Residue |
| B | ARG119 |
| B | GLN123 |
| C | THR123 |
Functional Information from PROSITE/UniProt
| site_id | PS00128 |
| Number of Residues | 19 |
| Details | GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. ChlsCsaLlqdNIadavaC |
| Chain | Residue | Details |
| A | CYS77-CYS95 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 258 |
| Details | Domain: {"description":"C-type lysozyme","evidences":[{"source":"PROSITE-ProRule","id":"PRU00680","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {} |
| Chain | Residue | Details |
