Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006952 | biological_process | defense response |
| A | 0008200 | molecular_function | ion channel inhibitor activity |
| A | 0017080 | molecular_function | sodium channel regulator activity |
| A | 0019871 | molecular_function | sodium channel inhibitor activity |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0090729 | molecular_function | toxin activity |
| A | 0099106 | molecular_function | ion channel regulator activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD A 101 |
| Chain | Residue |
| A | TRP39 |
| A | ILE40 |
| A | GLY41 |
| A | GLU55 |
| A | MPD102 |
| A | HOH221 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MPD A 102 |
| Chain | Residue |
| A | TRP39 |
| A | ILE40 |
| A | MPD101 |
| A | MPD103 |
| A | TYR6 |
| A | LYS29 |
| A | ASN30 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE MPD A 103 |
| Chain | Residue |
| A | ILE7 |
| A | ALA8 |
| A | ASP9 |
| A | ASP10 |
| A | ASP10 |
| A | TYR15 |
| A | ASN30 |
| A | VAL56 |
| A | MPD102 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 62 |
| Details | Domain: {"description":"LCN-type CS-alpha/beta","evidences":[{"source":"PROSITE-ProRule","id":"PRU01210","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Motif: {"description":"Important for toxin selectivity for individual Nav channel subtype (Nav1.6/SCN8A and Nav1.7/SCN9A), but not for toxin potency","evidences":[{"source":"PubMed","id":"23527544","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for toxin potency but not for selectivity for individual Nav channel subtype (Nav1.6/SCN8A and Nav1.7/SCN9A)","evidences":[{"source":"PubMed","id":"23527544","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Arginine amide","evidences":[{"source":"PubMed","id":"16038905","evidenceCode":"ECO:0000269"}]} |
