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4HEE

Crystal structure of PPARgamma in complex with compound 13

Functional Information from GO Data
ChainGOidnamespacecontents
X0003677molecular_functionDNA binding
X0004879molecular_functionnuclear receptor activity
X0005634cellular_componentnucleus
X0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues13
DetailsBINDING SITE FOR RESIDUE 14R X 501
ChainResidue
XGLY284
XILE341
XSER342
XLYS367
XHIS449
XCYS285
XARG288
XSER289
XHIS323
XILE326
XTYR327
XVAL339
XLEU340

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
YSER698
XHIS323
XHIS449
XTYR473

site_idSWS_FT_FI2
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649
ChainResidueDetails
XLYS224

218853

PDB entries from 2024-04-24

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