Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | ALA96 |
| A | ASP97 |
| A | THR97 |
| A | TYR127 |
| A | THR178 |
| A | LYS179 |
| A | HIS233 |
| A | HOH459 |
| A | HOH507 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | LYS62 |
| A | ASN87 |
| A | GLN170 |
| A | PRO170 |
| A | HIS170 |
| A | HOH433 |
| A | HOH525 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 303 |
| Chain | Residue |
| A | SER48 |
| A | PRO49 |
| A | CYS50 |
| A | HOH593 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 304 |
| Chain | Residue |
| A | ARG217 |
| A | GLY218 |
| A | HOH688 |
| B | GLY4 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 305 |
| Chain | Residue |
| A | GLU25 |
| A | SER71 |
| A | THR77 |
| A | HOH462 |
| A | HOH481 |
| A | HOH563 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 306 |
| Chain | Residue |
| A | ILE163 |
| A | HIS165 |
| A | LEU181 |
| A | CYS182 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 307 |
| Chain | Residue |
| A | ASN101 |
| A | HOH498 |
| A | HOH600 |
| A | HOH648 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 308 |
| Chain | Residue |
| A | ARG35 |
| A | HIS37 |
| A | ARG37 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 309 |
| Chain | Residue |
| A | SER164 |
| A | HIS165 |
| A | HOH436 |
| A | HOH492 |
| A | HOH601 |
| site_id | BC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE P6G A 310 |
| Chain | Residue |
| A | VAL38 |
| A | THR39 |
| A | TYR40 |
| A | ASN74 |
| A | SER135 |
| A | TYR149 |
| A | TYR151 |
| A | SER202 |
| A | HOH458 |
| A | HOH474 |
| A | HOH605 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 311 |
| Chain | Residue |
| A | GLU167 |
| A | GLN170 |
| A | TYR171 |
| A | LYS223 |
| A | ASP223 |
| A | HOH623 |
| site_id | BC3 |
| Number of Residues | 38 |
| Details | BINDING SITE FOR CHAIN B OF BICYCLIC PEPTIDE INHIBITOR UK504 |
| Chain | Residue |
| B | HOH111 |
| B | HOH113 |
| A | ARG35 |
| A | VAL41 |
| A | HIS57 |
| A | CYS58 |
| A | ASP60 |
| A | TYR60 |
| A | TYR64 |
| A | ASP97 |
| A | THR97 |
| A | LEU97 |
| A | HIS99 |
| A | ASP189 |
| A | SER190 |
| A | GLN192 |
| A | GLY193 |
| A | SER195 |
| A | SER214 |
| A | GLY216 |
| A | ARG217 |
| A | GLY218 |
| A | CYS220 |
| A | LYS224 |
| A | GLY226 |
| A | CL304 |
| A | HOH423 |
| A | HOH478 |
| A | HOH550 |
| A | HOH580 |
| A | HOH685 |
| B | HOH101 |
| B | HOH102 |
| B | HOH103 |
| B | HOH104 |
| B | HOH106 |
| B | HOH108 |
| B | HOH110 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. ISATHC |
| Chain | Residue | Details |
| A | ILE53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"9151681","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000026"} |
