Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0006265 | biological_process | DNA topological change |
| F | 0003677 | molecular_function | DNA binding |
| F | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0006259 | biological_process | DNA metabolic process |
| F | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 1201 |
| Chain | Residue |
| A | GLU66 |
| A | ASN70 |
| A | ANP1202 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ANP A 1202 |
| Chain | Residue |
| A | PHE121 |
| A | THR126 |
| A | SER127 |
| A | SER128 |
| A | ASN129 |
| A | GLY140 |
| A | ARG141 |
| A | ASN142 |
| A | GLY143 |
| A | TYR144 |
| A | GLY145 |
| A | ALA146 |
| A | LYS147 |
| A | THR195 |
| A | GLN365 |
| A | LYS367 |
| A | MG1201 |
| A | ASN70 |
| A | ASN74 |
| A | ARG77 |
| A | ASN99 |
| A | ILE104 |
| A | ILE120 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG F 1201 |
| Chain | Residue |
| F | GLU66 |
| F | ASN70 |
| F | ANP1202 |
| site_id | AC4 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ANP F 1202 |
| Chain | Residue |
| F | ASN70 |
| F | ASN74 |
| F | ARG77 |
| F | ASN99 |
| F | ILE104 |
| F | ILE120 |
| F | PHE121 |
| F | THR126 |
| F | SER127 |
| F | SER128 |
| F | ASN129 |
| F | GLY140 |
| F | ARG141 |
| F | ASN142 |
| F | GLY143 |
| F | TYR144 |
| F | GLY145 |
| F | ALA146 |
| F | LYS147 |
| F | THR195 |
| F | GLN365 |
| F | LYS367 |
| F | MG1201 |
Functional Information from PROSITE/UniProt
| site_id | PS00177 |
| Number of Residues | 9 |
| Details | TOPOISOMERASE_II DNA topoisomerase II signature. LTEGDSALS |
| Chain | Residue | Details |
| A | LEU447-SER455 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | PTR782 | |
| F | PTR782 | |
| Chain | Residue | Details |
| A | ASN70 | |
| F | GLN365 | |
| A | ASN99 | |
| A | SER127 | |
| A | GLY140 | |
| A | GLN365 | |
| F | ASN70 | |
| F | ASN99 | |
| F | SER127 | |
| F | GLY140 | |
| Chain | Residue | Details |
| A | GLU449 | |
| A | ASP526 | |
| A | ASP528 | |
| F | GLU449 | |
| F | ASP526 | |
| F | ASP528 | |
| Chain | Residue | Details |
| A | LYS477 | |
| A | TYR734 | |
| A | SER740 | |
| A | TRP908 | |
| F | LYS477 | |
| F | TYR734 | |
| F | SER740 | |
| F | TRP908 | |
| Chain | Residue | Details |
| A | ASN480 | |
| A | ARG650 | |
| A | LYS651 | |
| A | LYS700 | |
| F | ASN480 | |
| F | ARG650 | |
| F | LYS651 | |
| F | LYS700 | |
| Chain | Residue | Details |
| A | ARG781 | |
| F | ARG781 | |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | SITE: Important for DNA bending; intercalates between base pairs of target DNA => ECO:0000269|PubMed:18097402 |
| Chain | Residue | Details |
| A | ILE833 | |
| F | ILE833 | |
| Chain | Residue | Details |
| A | THR1086 | |
| F | THR1086 | |
| Chain | Residue | Details |
| A | SER1087 | |
| F | SER1087 | |
