4GCW
Crystal structure of RNase Z in complex with precursor tRNA(Thr)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0008033 | biological_process | tRNA processing |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016891 | molecular_function | RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism |
| A | 0042780 | biological_process | tRNA 3'-end processing |
| A | 0042781 | molecular_function | 3'-tRNA processing endoribonuclease activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | ASP67 |
| A | HIS68 |
| A | ASP211 |
| A | HIS269 |
| A | ZN402 |
| B | OMU74 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 402 |
| Chain | Residue |
| A | ASP211 |
| A | ZN401 |
| B | OMU74 |
| A | HIS63 |
| A | HIS65 |
| A | HIS140 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MES A 403 |
| Chain | Residue |
| A | ARG54 |
| A | ASP86 |
| B | U4 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_01818","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15654328","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01818","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15654328","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01818","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15654328","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16518398","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
