4F2C
The Crystal Structure of a Human MitoNEET double mutant in which Gly 66 are Asp 67 are both Replaced with Ala Residues
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0010506 | biological_process | regulation of autophagy |
| A | 0043231 | cellular_component | intracellular membrane-bounded organelle |
| A | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| B | 0010506 | biological_process | regulation of autophagy |
| B | 0043231 | cellular_component | intracellular membrane-bounded organelle |
| B | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FES A 201 |
| Chain | Residue |
| A | CYS72 |
| A | ARG73 |
| A | CYS74 |
| A | CYS83 |
| A | ASP84 |
| A | ALA86 |
| A | HIS87 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FES B 201 |
| Chain | Residue |
| B | CYS74 |
| B | CYS83 |
| B | ASP84 |
| B | GLY85 |
| B | ALA86 |
| B | HIS87 |
| B | CYS72 |
| B | ARG73 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Schiff-base intermediate with pyridoxal 5'-phosphate","evidences":[{"source":"PubMed","id":"36194135","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17766439","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17766440","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17905743","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QD0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QH7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2R13","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q91WS0","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 13 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"25621951","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"25621951","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
