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4DK7

Crystal structure of LXR ligand binding domain in complex with full agonist 1

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0006629biological_processlipid metabolic process
C0003677molecular_functionDNA binding
C0004879molecular_functionnuclear receptor activity
C0006629biological_processlipid metabolic process
Functional Information from PDB Data
site_idAC1
Number of Residues15
DetailsBINDING SITE FOR RESIDUE 0KS A 501
ChainResidue
ATHR272
AHIS435
AGLN438
ALEU442
ALEU449
ALEU453
ATRP457
AALA275
ASER278
ALEU313
ATHR316
APHE329
APHE340
ALEU345
APHE349

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE ACT A 502
ChainResidue
AGLU325
ALYS337
AARG358
ACA505
ACA505
AHOH643

site_idAC3
Number of Residues2
DetailsBINDING SITE FOR RESIDUE CA A 503
ChainResidue
AGLN235
AGLU281

site_idAC4
Number of Residues1
DetailsBINDING SITE FOR RESIDUE CA A 504
ChainResidue
ATHR334

site_idAC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE CA A 505
ChainResidue
AGLU325
AGLU325
AACT502
AACT502

site_idAC6
Number of Residues2
DetailsBINDING SITE FOR RESIDUE CA A 506
ChainResidue
AASP339
AASP339

site_idAC7
Number of Residues16
DetailsBINDING SITE FOR RESIDUE 0KS C 501
ChainResidue
CTHR272
CLEU274
CALA275
CSER278
CMSE312
CLEU313
CTHR316
CPHE329
CPHE340
CLEU345
CHIS435
CGLN438
CVAL439
CLEU442
CTRP457
CHOH637

site_idAC8
Number of Residues2
DetailsBINDING SITE FOR RESIDUE CA C 503
ChainResidue
CTHR334
CASP339

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000269|PubMed:20159957
ChainResidueDetails
ALYS410
ALYS448
CLYS410
CLYS448

226707

PDB entries from 2024-10-30

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