Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| A | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| A | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
| B | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| B | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 601 |
| Chain | Residue |
| A | GLN269 |
| A | LYS350 |
| A | THR351 |
| A | GOL607 |
| A | HOH817 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 602 |
| Chain | Residue |
| A | ASP443 |
| A | GLY444 |
| A | GLU478 |
| A | ASP498 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 603 |
| Chain | Residue |
| A | PRO226 |
| A | GLU233 |
| A | HIS235 |
| A | HOH812 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 604 |
| Chain | Residue |
| A | VAL442 |
| A | VAL496 |
| A | ASP498 |
| A | ILE542 |
| A | GLY543 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 605 |
| Chain | Residue |
| A | GLU44 |
| A | LYS46 |
| A | SER117 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 606 |
| Chain | Residue |
| A | LYS103 |
| A | PRO176 |
| A | ASP177 |
| A | ILE178 |
| A | VAL179 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 607 |
| Chain | Residue |
| A | HIS96 |
| A | TRP239 |
| A | GLN269 |
| A | ILE270 |
| A | VAL314 |
| A | HIS315 |
| A | LEU349 |
| A | LYS350 |
| A | THR351 |
| A | MG601 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 608 |
| Chain | Residue |
| A | TYR532 |
| A | ALA534 |
| A | TRP535 |
| B | ASN255 |
| B | GLN258 |
| B | LYS259 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 609 |
| Chain | Residue |
| A | THR7 |
| A | ASP121 |
| A | GLU122 |
| A | ASP123 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 610 |
| Chain | Residue |
| A | THR386 |
| B | THR27 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 611 |
| Chain | Residue |
| A | LYS395 |
| A | GLU396 |
| A | GLU399 |
| A | HOH747 |
| A | HOH809 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 612 |
| Chain | Residue |
| A | GLN197 |
| A | LYS201 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 613 |
| Chain | Residue |
| A | LYS101 |
| A | LYS103 |
| A | VAL106 |
| A | TYR188 |
| A | HIS235 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 614 |
| Chain | Residue |
| A | GLU370 |
| A | GLN373 |
| A | LYS374 |
| A | THR377 |
| B | GLU396 |
| B | THR400 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 615 |
| Chain | Residue |
| A | THR377 |
| B | PRO25 |
| B | THR400 |
| B | EDO504 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 501 |
| Chain | Residue |
| B | GLN23 |
| B | ASN57 |
| B | THR58 |
| B | THR131 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 502 |
| Chain | Residue |
| A | TRP406 |
| B | GLN330 |
| B | LYS331 |
| B | PRO392 |
| B | VAL423 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 503 |
| Chain | Residue |
| B | PRO157 |
| B | TYR183 |
| B | MET184 |
| B | HOH604 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 504 |
| Chain | Residue |
| A | EDO615 |
| B | TRP24 |
| B | GLU399 |
| B | TRP402 |
| B | HOH646 |
| B | HOH704 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 505 |
| Chain | Residue |
| B | ARG358 |
| B | LYS366 |
| B | GLU370 |
| B | TYR405 |
| B | GLN407 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 506 |
| Chain | Residue |
| B | TRP406 |
| B | LYS30 |
| B | LYS64 |
| B | TRP71 |
| B | THR403 |
| B | GLU404 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 507 |
| Chain | Residue |
| A | HIS315 |
| A | PHE346 |
| A | LYS347 |
| A | ASN348 |
| B | TYR318 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 508 |
| Chain | Residue |
| A | GLU6 |
| A | THR7 |
| B | GLU53 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 509 |
| Chain | Residue |
| B | GLY45 |
| B | PRO119 |
| B | ARG125 |
| B | ASN147 |
| B | HOH707 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 190 |
| Details | Domain: {"description":"Reverse transcriptase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00405","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Region: {"description":"RT 'primer grip'"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 32 |
| Details | Motif: {"description":"Tryptophan repeat motif"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Site: {"description":"Essential for RT p66/p51 heterodimerization"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by viral protease; partial"} |
