Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0006957 | biological_process | complement activation, alternative pathway |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0009617 | biological_process | response to bacterium |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005615 | cellular_component | extracellular space |
| B | 0006508 | biological_process | proteolysis |
| B | 0006957 | biological_process | complement activation, alternative pathway |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0009617 | biological_process | response to bacterium |
| B | 0046872 | molecular_function | metal ion binding |
| D | 0005576 | cellular_component | extracellular region |
| D | 0005615 | cellular_component | extracellular space |
| D | 0006955 | biological_process | immune response |
| D | 0046872 | molecular_function | metal ion binding |
| L | 0005576 | cellular_component | extracellular region |
| L | 0005615 | cellular_component | extracellular space |
| L | 0006955 | biological_process | immune response |
| L | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 301 |
| Chain | Residue |
| A | ASP129 |
| H | TYR54 |
| A | VAL130 |
| A | VAL162 |
| A | LEU163 |
| A | ASP164 |
| A | ARG165 |
| A | MET181 |
| A | CYS182 |
| A | HOH492 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 302 |
| Chain | Residue |
| A | ASN222 |
| A | LYS223 |
| A | LYS224 |
| L | ASP30 |
| L | ASP31 |
| L | ASP32 |
| L | ZN302 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN A 303 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 304 |
| Chain | Residue |
| A | ARG150 |
| A | PRO152 |
| A | ASP153 |
| A | ARG154 |
| A | HOH500 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 305 |
| Chain | Residue |
| A | SER190 |
| A | SER195 |
| A | THR214 |
| A | ARG218 |
| A | HOH515 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL B 301 |
| Chain | Residue |
| B | ASP129 |
| B | VAL130 |
| B | VAL162 |
| B | LEU163 |
| B | ASP164 |
| B | ARG165 |
| B | MET181 |
| B | CYS182 |
| B | HOH445 |
| E | TYR54 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 302 |
| Chain | Residue |
| B | LEU135 |
| B | LEU159 |
| B | VAL200 |
| B | CYS201 |
| B | GLY202 |
| B | GLY207 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 303 |
| Chain | Residue |
| B | GLN125 |
| B | ARG129 |
| B | ASP129 |
| B | GLU210 |
| B | HOH412 |
| B | HOH436 |
| B | HOH437 |
| B | HOH439 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B 304 |
| Chain | Residue |
| A | HIS25 |
| A | GLU77 |
| B | GLU131 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 305 |
| Chain | Residue |
| B | ARG150 |
| B | PRO152 |
| B | ASP153 |
| B | ARG154 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 301 |
| Chain | Residue |
| B | ARG170 |
| B | THR170 |
| B | LYS224 |
| D | ASP31 |
| D | ASP32 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL D 302 |
| Chain | Residue |
| D | LEU54 |
| D | ARG55 |
| D | GLY57 |
| D | VAL58 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN D 303 |
| Chain | Residue |
| A | HIS146 |
| A | HOH407 |
| D | ASP1 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN D 304 |
| Chain | Residue |
| D | ASN138 |
| E | HIS172 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL E 301 |
| Chain | Residue |
| A | GLY202 |
| A | HOH440 |
| E | LYS19 |
| E | SER71 |
| E | LEU72 |
| E | HOH450 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL E 302 |
| Chain | Residue |
| E | ARG38 |
| E | GLU46 |
| E | ASP63 |
| E | ARG67 |
| E | PHE68 |
| E | HOH485 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL H 301 |
| Chain | Residue |
| H | GLN113 |
| H | GLY114 |
| H | THR115 |
| H | LEU116 |
| H | PRO157 |
| H | HOH433 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN H 302 |
| Chain | Residue |
| H | HIS172 |
| L | ASN138 |
| site_id | CC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN L 301 |
| Chain | Residue |
| D | HOH505 |
| L | ASP28 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN L 302 |
| Chain | Residue |
| A | GOL302 |
| L | ASP31 |
| L | ASP32 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LSAAHC |
| Chain | Residue | Details |
| A | LEU53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPLV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| E | TYR202-HIS208 | |
| D | TYR192-HIS198 | |
