4D2H
Crystal structure of the tetramerisation domain of human CtIP
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 G 1053 |
| Chain | Residue |
| D | VAL40 |
| D | LYS44 |
| G | LYS44 |
| G | HOH2018 |
| G | HOH2019 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1050 |
| Chain | Residue |
| B | LYS21 |
| B | HOH2013 |
| C | LYS28 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1051 |
| Chain | Residue |
| E | LYS44 |
| B | LYS44 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1052 |
| Chain | Residue |
| A | LYS46 |
| B | LYS41 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 H 1052 |
| Chain | Residue |
| H | LYS41 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 G 1054 |
| Chain | Residue |
| F | LYS28 |
| G | LYS21 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 F 1053 |
| Chain | Residue |
| F | HOH2013 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 F 1054 |
| Chain | Residue |
| A | SER18 |
| A | HOH2003 |
| F | SER18 |
| F | PHE20 |
| F | HOH2001 |
| F | HOH2015 |
| G | HIS31 |
| H | GLU34 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 F 1055 |
| Chain | Residue |
| F | LYS21 |
| G | LYS28 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1053 |
| Chain | Residue |
| A | GLU34 |
| B | HIS31 |
| C | PHE20 |
| C | LYS21 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1049 |
| Chain | Residue |
| A | HIS31 |
| B | GLU34 |
| D | ASP19 |
| D | PHE20 |
| D | LYS21 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E 1049 |
| Chain | Residue |
| E | ASP19 |
| E | PHE20 |
| E | LYS21 |
| G | GLU34 |
| H | HIS31 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 G 1055 |
| Chain | Residue |
| E | GLU34 |
| F | HIS31 |
| F | HOH2002 |
| G | SER18 |
| G | ASP19 |
| G | PHE20 |
| G | LYS21 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1052 |
| Chain | Residue |
| B | SER18 |
| B | PHE20 |
| B | LYS21 |
| B | HOH2001 |
| C | HIS31 |
| D | GLU34 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 184 |
| Details | Region: {"description":"Essential for binding to the MRN complex and for RPA focus formation on DNA damage"} |
| Chain | Residue | Details |
