4CU4
FhuA from E. coli in complex with the lasso peptide microcin J25 (MccJ25)
Functional Information from GO Data
Functional Information from PROSITE/UniProt
| site_id | PS01156 |
| Number of Residues | 18 |
| Details | TONB_DEPENDENT_REC_2 TonB-dependent receptor (TBDR) proteins signature 2. GcfwGaERqVvATAtFrF |
| Chain | Residue | Details |
| A | GLY708-PHE725 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 177 |
| Details | Transmembrane: {"description":"Beta stranded"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 239 |
| Details | Topological domain: {"description":"Extracellular"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 46 |
| Details | Topological domain: {"description":"Periplasmic"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 112 |
| Details | Domain: {"description":"TBDR plug","evidences":[{"source":"PROSITE-ProRule","id":"PRU01360","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 17 |
| Details | Motif: {"description":"TonB C-terminal box"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10850805","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9856937","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9865695","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9856937","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interaction with phage T5 RBP-pb5","evidences":[{"source":"PubMed","id":"36779755","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | Peptide: {"description":"Microcin J25","featureId":"PRO_0000002775","evidences":[{"source":"PubMed","id":"10092860","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 5 |
| Details | Site: {"description":"Essential for permeation into bacteria","evidences":[{"source":"PubMed","id":"18632663","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Site: {"description":"Essential for permeation into bacteria and for RNAP inhibition","evidences":[{"source":"PubMed","id":"18632663","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Isoglutamyl glycine isopeptide (Gly-Glu)","evidences":[{"source":"PubMed","id":"14531661","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14531690","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14531691","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
