Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | HIS135 |
| A | HIS139 |
| A | GLU159 |
| A | RDF501 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 402 |
| Chain | Residue |
| A | HOH2170 |
| A | HOH2193 |
| A | ASP129 |
| A | ASP131 |
| A | GLN170 |
| A | ASP178 |
| A | ASP179 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 403 |
| Chain | Residue |
| A | ASP53 |
| A | ASP55 |
| A | VAL57 |
| A | HOH2099 |
| A | HOH2101 |
| B | HOH2038 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 404 |
| Chain | Residue |
| A | TYR181 |
| A | THR182 |
| A | ILE185 |
| A | ASP188 |
| A | HOH2201 |
| A | HOH2203 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE RDF A 501 |
| Chain | Residue |
| A | ASN104 |
| A | ASN105 |
| A | ALA106 |
| A | PHE123 |
| A | HIS135 |
| A | GLU136 |
| A | HIS139 |
| A | GLU159 |
| A | LEU190 |
| A | ARG191 |
| A | HIS219 |
| A | ZN401 |
| A | HOH2159 |
| A | HOH2314 |
| A | HOH2315 |
| B | ASN215 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 401 |
| Chain | Residue |
| B | HIS135 |
| B | HIS139 |
| B | GLU159 |
| B | RDF501 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 402 |
| Chain | Residue |
| B | ASP129 |
| B | ASP131 |
| B | GLN170 |
| B | ASP178 |
| B | HOH2155 |
| B | HOH2179 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 403 |
| Chain | Residue |
| B | ASP53 |
| B | ASP55 |
| B | VAL57 |
| B | HOH2083 |
| B | HOH2084 |
| B | HOH2088 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 404 |
| Chain | Residue |
| B | TYR181 |
| B | THR182 |
| B | ILE185 |
| B | ASP188 |
| B | HOH2187 |
| B | HOH2191 |
| site_id | BC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE RDF B 501 |
| Chain | Residue |
| A | TYR151 |
| A | ASN215 |
| A | HOH2183 |
| A | HOH2247 |
| B | ASN104 |
| B | ASN105 |
| B | ALA106 |
| B | PHE123 |
| B | PHE126 |
| B | HIS135 |
| B | GLU136 |
| B | HIS139 |
| B | GLU159 |
| B | LEU190 |
| B | ARG191 |
| B | HIS219 |
| B | ZN401 |
| B | HOH2274 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 1305 |
| Chain | Residue |
| A | ASN109 |
| A | HOH2161 |
| A | HOH2162 |
| A | HOH2316 |
| B | GLU149 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VVGHELTHGV |
| Chain | Residue | Details |
| A | VAL132-VAL141 | |
