Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1385 |
| Chain | Residue |
| A | ARG96 |
| A | ARG180 |
| A | LYS205 |
| A | ASN213 |
| A | VAL214 |
| A | HOH2168 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1385 |
| Chain | Residue |
| B | ASN213 |
| B | VAL214 |
| B | ARG96 |
| B | ARG180 |
| B | LYS205 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1386 |
| Chain | Residue |
| B | ARG96 |
| B | HOH2064 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1386 |
| Chain | Residue |
| A | ARG96 |
| A | HOH2062 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1387 |
| Chain | Residue |
| A | VAL208 |
| A | ARG209 |
| A | HOH2063 |
| A | HOH2066 |
| B | ARG209 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1387 |
| Chain | Residue |
| B | ARG278 |
| B | HOH2114 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 1388 |
| Chain | Residue |
| B | PRO154 |
| B | VAL155 |
| B | ILE156 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 1388 |
| Chain | Residue |
| A | PRO154 |
| A | VAL155 |
| A | HOH2169 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 1389 |
| Chain | Residue |
| A | TYR56 |
| A | TYR71 |
| A | LYS86 |
| A | ASN129 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 1389 |
| Chain | Residue |
| B | ARG144 |
| B | SER147 |
| B | GLU249 |
| B | GLY253 |
| B | GLN254 |
| B | HOH2098 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 1390 |
| Chain | Residue |
| A | SER215 |
| A | PTR216 |
| A | LEU227 |
| A | ILE228 |
| A | GLY230 |
| A | HOH2072 |
| A | HOH2074 |
| X | LEU203 |
| X | VAL207 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 1390 |
| Chain | Residue |
| B | THR138 |
| B | GLN185 |
| B | ASN186 |
| B | LEU188 |
| B | SJJ1392 |
| B | HOH2033 |
| B | HOH2059 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 1391 |
| Chain | Residue |
| B | TYR56 |
| B | TYR71 |
| B | LYS86 |
| B | ASN129 |
| site_id | BC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SJJ A 1391 |
| Chain | Residue |
| A | ALA83 |
| A | LYS85 |
| A | LEU132 |
| A | ASP133 |
| A | TYR134 |
| A | VAL135 |
| A | PRO136 |
| A | LEU188 |
| A | ASP200 |
| site_id | BC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SJJ B 1392 |
| Chain | Residue |
| B | PHE67 |
| B | VAL70 |
| B | ALA83 |
| B | LYS85 |
| B | LEU132 |
| B | ASP133 |
| B | TYR134 |
| B | VAL135 |
| B | PRO136 |
| B | LEU188 |
| B | ASP200 |
| B | GOL1390 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 25 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGNGSFGVVYqAklcdsgelv.........AIKK |
| Chain | Residue | Details |
| A | ILE62-LYS86 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IcHrDIKpqNLLL |
| Chain | Residue | Details |
| A | ILE177-LEU189 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17050006","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"12554650","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25169422","evidenceCode":"ECO:0000269"}]} |
