Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3ZE3

Crystal structure of the integral membrane diacylglycerol kinase - delta7

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016021	cellular_component	integral component of membrane
A	0016020	cellular_component	membrane
A	0005886	cellular_component	plasma membrane
A	0005524	molecular_function	ATP binding
A	0004143	molecular_function	diacylglycerol kinase activity
A	0006654	biological_process	phosphatidic acid biosynthetic process
A	0009411	biological_process	response to UV
B	0016021	cellular_component	integral component of membrane
B	0016020	cellular_component	membrane
B	0005886	cellular_component	plasma membrane
B	0005524	molecular_function	ATP binding
B	0004143	molecular_function	diacylglycerol kinase activity
B	0006654	biological_process	phosphatidic acid biosynthetic process
B	0009411	biological_process	response to UV
C	0016021	cellular_component	integral component of membrane
C	0016020	cellular_component	membrane
C	0005886	cellular_component	plasma membrane
C	0005524	molecular_function	ATP binding
C	0004143	molecular_function	diacylglycerol kinase activity
C	0006654	biological_process	phosphatidic acid biosynthetic process
C	0009411	biological_process	response to UV
D	0016021	cellular_component	integral component of membrane
D	0016020	cellular_component	membrane
D	0005886	cellular_component	plasma membrane
D	0005524	molecular_function	ATP binding
D	0004143	molecular_function	diacylglycerol kinase activity
D	0006654	biological_process	phosphatidic acid biosynthetic process
D	0009411	biological_process	response to UV
E	0016021	cellular_component	integral component of membrane
E	0016020	cellular_component	membrane
E	0005886	cellular_component	plasma membrane
E	0005524	molecular_function	ATP binding
E	0004143	molecular_function	diacylglycerol kinase activity
E	0006654	biological_process	phosphatidic acid biosynthetic process
E	0009411	biological_process	response to UV
F	0016021	cellular_component	integral component of membrane
F	0016020	cellular_component	membrane
F	0005886	cellular_component	plasma membrane
F	0005524	molecular_function	ATP binding
F	0004143	molecular_function	diacylglycerol kinase activity
F	0006654	biological_process	phosphatidic acid biosynthetic process
F	0009411	biological_process	response to UV

Functional Information from PDB Data

site_id

Number of Residues

Details

AC1

BINDING SITE FOR RESIDUE NA F 1122

Chain	Residue
D	LEU64
D	ASP107
D	HOH2044
F	SER60
F	LEU64
F	HOH2024

AC2

BINDING SITE FOR RESIDUE NA E 1122

Chain	Residue
D	SER60
E	SER61
E	THR111
E	HOH2020

AC3

BINDING SITE FOR RESIDUE ZN D 1122

Chain	Residue
D	GLU28
D	GLU76
D	FLC1123
D	ACT1124

AC4

BINDING SITE FOR RESIDUE FLC D 1123

Chain	Residue
D	GLU76
D	ZN1122
D	ACT1124
D	HOH2048

AC5

BINDING SITE FOR RESIDUE ACT D 1124

Chain	Residue
D	GLU28
D	GLU69
D	ASN72
D	SER73
D	GLU76
D	ZN1122
D	FLC1123
D	HOH2047

AC6

BINDING SITE FOR RESIDUE 78N B 1122

Chain	Residue
A	ALA13
A	ALA14
A	SER17
A	78N1123
A	78N1124
B	SER98
B	VAL101
B	LEU102
B	ILE105
B	ILE110
B	78N1123

AC7

BINDING SITE FOR RESIDUE 78N B 1123

Chain	Residue
A	ARG9
A	78N1124
B	GLU34
B	VAL65
B	GLU69
B	ALA108
B	TRP112
B	ALA113
B	78N1122

AC8

BINDING SITE FOR RESIDUE 78M D 1125

Chain	Residue
A	GLN33
A	GLU34
A	78M1126
C	TRP117
C	78N1122
D	TRP25
D	ALA29
D	ARG32
D	GLN33
D	VAL36
D	HOH2017
D	HOH2049

AC9

BINDING SITE FOR RESIDUE 78N C 1122

Chain	Residue
A	78M1126
B	ALA46
B	ARG55
B	HOH2010
C	ILE110
C	ILE114
C	TRP117
C	SER118
D	GLN33
D	78M1125

BC1

BINDING SITE FOR RESIDUE 78N A 1122

Chain	Residue
A	TRP18
A	ARG22
A	TRP25
A	ILE26
A	LEU39
A	MET63
A	MET66

BC2

BINDING SITE FOR RESIDUE 78M D 1126

Chain	Residue
A	ALA30
A	PHE31
A	GLU34
A	GLU69
A	LEU102
A	ILE105
A	HOH2012
D	ARG22
D	TRP25
D	HOH2050

BC3

BINDING SITE FOR RESIDUE 78M D 1127

Chain	Residue
B	TRP47
B	HOH2006
B	HOH2008
D	LEU102
D	VAL109
D	ALA113
D	HOH2018
D	HOH2043

BC4

BINDING SITE FOR RESIDUE 78N C 1123

Chain	Residue
A	LEU40
A	TRP47
A	78M1126
C	GLU34
C	GLU69
C	TRP112

BC5

BINDING SITE FOR RESIDUE 78M D 1128

Chain	Residue
A	TRP117
B	GLY35
B	VAL36
D	TRP47
D	LEU48
D	ASP49
D	PHE120

BC6

BINDING SITE FOR RESIDUE 78N A 1123

Chain	Residue
A	VAL42
A	ALA46
A	ARG55
A	78N1124
A	HOH2016
B	78N1122

BC7

BINDING SITE FOR RESIDUE 78N A 1124

Chain	Residue
A	VAL50
A	ASP51
A	ALA52
A	ARG55
A	78N1123
B	ILE114
B	TRP117
B	78N1122
B	78N1123

BC8

BINDING SITE FOR RESIDUE 78M A 1125

Chain	Residue
A	ILE110
A	TRP117
D	ALA46
D	TRP47
D	ARG55

BC9

BINDING SITE FOR RESIDUE 78M A 1126

Chain	Residue
A	CYS41
A	PHE120
A	HOH2015
C	LEU102
C	ILE105
C	78N1122
C	78N1123
D	LEU39
D	78M1125

Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_id

Number of Residues

Details

Functional Information from PROSITE/UniProt

site_id

Number of Residues

Details

PS01069

Prokaryotic diacylglycerol kinase signature.E-x-[LIVM]-N-[ST]-[SA]-[LIV]-E-x(2)-V-D.

Chain	Residue	Details
A	GLU69-ASP80
B	GLU69-ASP80
C	GLU69-ASP80
D	GLU69-ASP80
E	GLU69-ASP80
F	GLU69-ASP80

Functional Information from SwissProt/UniProt

site_id

Number of Residues

Details

Catalytic Information from CSA

site_id

Number of Residues

Details

English ▼

167132

entries
(2020-07-29)

167132

PDB entries from 2020-07-29

		Sequence (fasta)
		PDBx/mmCIF
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