Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005507 | molecular_function | copper ion binding |
| A | 0008131 | molecular_function | primary amine oxidase activity |
| A | 0009308 | biological_process | amine metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0048038 | molecular_function | quinone binding |
| A | 0052595 | molecular_function | aliphatic amine oxidase activity |
| B | 0005507 | molecular_function | copper ion binding |
| B | 0008131 | molecular_function | primary amine oxidase activity |
| B | 0009308 | biological_process | amine metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0048038 | molecular_function | quinone binding |
| B | 0052595 | molecular_function | aliphatic amine oxidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CU A 701 |
| Chain | Residue |
| A | HIS431 |
| A | HIS433 |
| A | HIS592 |
| A | BR702 |
| A | HOH1154 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BR A 702 |
| Chain | Residue |
| A | MET602 |
| A | CU701 |
| A | 2TY382 |
| A | HIS431 |
| A | HIS433 |
| A | HIS592 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BR A 703 |
| Chain | Residue |
| A | HIS345 |
| A | SER374 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BR A 704 |
| Chain | Residue |
| A | GLY34 |
| A | PRO35 |
| A | GLU36 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 705 |
| Chain | Residue |
| A | ASP440 |
| A | MET441 |
| A | ASP581 |
| A | ILE582 |
| A | HOH845 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE K A 706 |
| Chain | Residue |
| A | VAL79 |
| A | THR80 |
| A | ALA93 |
| A | ALA94 |
| A | ARG148 |
| A | SER562 |
| A | HOH1087 |
| A | HOH1138 |
| A | HOH1165 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 707 |
| Chain | Residue |
| A | THR521 |
| A | LEU522 |
| A | LEU523 |
| A | THR538 |
| A | HOH872 |
| B | ARG457 |
| B | HOH1053 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 708 |
| Chain | Residue |
| A | GLU347 |
| A | ARG370 |
| A | LYS401 |
| A | GOL711 |
| A | HOH946 |
| A | HOH1007 |
| A | HOH1169 |
| A | HOH1221 |
| B | HOH1060 |
| B | HOH1142 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 709 |
| Chain | Residue |
| A | ASN368 |
| A | TYR391 |
| A | ASP393 |
| A | GLU397 |
| A | LYS610 |
| A | HOH1171 |
| A | HOH1229 |
| B | HOH1059 |
| site_id | BC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 710 |
| Chain | Residue |
| A | ILE39 |
| A | TYR41 |
| A | LEU42 |
| A | VAL251 |
| A | GLN306 |
| A | SER329 |
| A | ASP330 |
| A | ALA331 |
| A | HOH887 |
| A | HOH896 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 711 |
| Chain | Residue |
| A | ARG370 |
| A | GLU397 |
| A | GLU399 |
| A | GOL708 |
| A | HOH1332 |
| B | GOL714 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 712 |
| Chain | Residue |
| A | ASP605 |
| A | HOH1187 |
| A | HOH1191 |
| B | HIS515 |
| B | LYS610 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 713 |
| Chain | Residue |
| A | GLU102 |
| A | THR378 |
| A | GLY380 |
| A | HOH827 |
| A | HOH1156 |
| A | HOH1157 |
| A | HOH1277 |
| B | LEU358 |
| site_id | BC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 714 |
| Chain | Residue |
| A | ALA15 |
| A | LEU42 |
| A | GLY43 |
| A | VAL44 |
| A | PHE249 |
| A | ASP250 |
| A | VAL251 |
| A | VAL327 |
| A | ILE328 |
| A | HOH929 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CU B 701 |
| Chain | Residue |
| B | HIS431 |
| B | HIS433 |
| B | HIS592 |
| B | BR702 |
| B | HOH1149 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BR B 702 |
| Chain | Residue |
| B | 2TY382 |
| B | HIS431 |
| B | HIS433 |
| B | MET602 |
| B | CU701 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BR B 703 |
| Chain | Residue |
| B | SER529 |
| B | ARG532 |
| B | SER562 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BR B 704 |
| Chain | Residue |
| B | HIS345 |
| B | SER374 |
| B | HOH962 |
| site_id | CC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BR B 705 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BR B 706 |
| Chain | Residue |
| B | GLY34 |
| B | PRO35 |
| B | GLU36 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 707 |
| Chain | Residue |
| B | ASP440 |
| B | MET441 |
| B | ASP581 |
| B | ILE582 |
| B | HOH815 |
| site_id | CC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE K B 708 |
| Chain | Residue |
| B | VAL79 |
| B | THR80 |
| B | ALA93 |
| B | ALA94 |
| B | SER562 |
| B | HOH952 |
| B | HOH1338 |
| site_id | CC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL B 709 |
| Chain | Residue |
| B | ARG532 |
| B | ARG533 |
| B | THR554 |
| B | PHE557 |
| B | HIS561 |
| B | SER562 |
| B | GLY563 |
| B | GLY564 |
| B | ALA565 |
| B | HOH819 |
| site_id | CC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 710 |
| Chain | Residue |
| A | ARG457 |
| B | THR521 |
| B | LEU522 |
| B | THR538 |
| B | HOH893 |
| B | HOH1192 |
| site_id | CC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 711 |
| Chain | Residue |
| B | GLU347 |
| B | ARG370 |
| B | LYS401 |
| B | GOL714 |
| B | HOH930 |
| B | HOH1060 |
| B | HOH1101 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 712 |
| Chain | Residue |
| B | ASP161 |
| B | VAL197 |
| B | HOH1083 |
| B | HOH1204 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 713 |
| Chain | Residue |
| A | LYS610 |
| B | LEU590 |
| B | ASP605 |
| B | THR606 |
| site_id | DC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 714 |
| Chain | Residue |
| A | GOL711 |
| B | ARG370 |
| B | TYR389 |
| B | TYR391 |
| B | GLU397 |
| B | GLU399 |
| B | GOL711 |
| site_id | DC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 715 |
| Chain | Residue |
| B | GLU102 |
| B | PHE105 |
| B | THR378 |
| B | GLY380 |
| B | HOH817 |
| B | HOH1260 |
| B | HOH1268 |
| site_id | DC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 716 |
| Chain | Residue |
| B | ILE39 |
| B | TYR41 |
| B | LEU42 |
| B | VAL251 |
| B | ILE328 |
| B | SER329 |
| B | ASP330 |
| B | HOH915 |
| site_id | DC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 717 |
| Chain | Residue |
| B | LEU42 |
| B | GLY43 |
| B | VAL44 |
| B | PHE249 |
| B | ASP250 |
| B | VAL251 |
| B | VAL327 |
| B | HOH1018 |
| B | HOH1373 |
Functional Information from PROSITE/UniProt
| site_id | PS01164 |
| Number of Residues | 14 |
| Details | COPPER_AMINE_OXID_1 Copper amine oxidase topaquinone signature. MVIsfftTigNYDY |
| Chain | Residue | Details |
| A | MET371-TYR384 | |
| site_id | PS01165 |
| Number of Residues | 14 |
| Details | COPPER_AMINE_OXID_2 Copper amine oxidase copper-binding site signature. TfGltHFprvEDwP |
| Chain | Residue | Details |
| A | THR587-PRO600 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP298 | |
| B | ASP298 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Schiff-base intermediate with substrate; via topaquinone => ECO:0000250|UniProtKB:P12807 |
| Chain | Residue | Details |
| A | 2TY382 | |
| B | 2TY382 | |
| Chain | Residue | Details |
| A | TYR296 | |
| B | TYR296 | |
| Chain | Residue | Details |
| A | ILE379 | |
| B | ILE379 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:9405045, ECO:0007744|PDB:1AV4, ECO:0007744|PDB:1AVL, ECO:0007744|PDB:1IU7, ECO:0007744|PDB:1IVU, ECO:0007744|PDB:1IVV, ECO:0007744|PDB:1IVW, ECO:0007744|PDB:1IVX, ECO:0007744|PDB:1RJO, ECO:0007744|PDB:1SIH, ECO:0007744|PDB:1SII, ECO:0007744|PDB:1UI8, ECO:0007744|PDB:1W4N, ECO:0007744|PDB:1W5Z, ECO:0007744|PDB:1W6C, ECO:0007744|PDB:1W6G, ECO:0007744|PDB:2BT3, ECO:0007744|PDB:2CFD, ECO:0007744|PDB:2CFG, ECO:0007744|PDB:2CFK, ECO:0007744|PDB:2CFL, ECO:0007744|PDB:2CFW, ECO:0007744|PDB:2CG0, ECO:0007744|PDB:2CG1, ECO:0007744|PDB:2CWT, ECO:0007744|PDB:2CWU, ECO:0007744|PDB:2CWV, ECO:0007744|PDB:2D1W, ECO:0007744|PDB:2E2T, ECO:0007744|PDB:2E2U, ECO:0007744|PDB:2E2V, ECO:0007744|PDB:2YX9, ECO:0007744|PDB:2ZL8, ECO:0007744|PDB:3AMO, ECO:0007744|PDB:3KII, ECO:0007744|PDB:3KN4, ECO:0007744|PDB:3WA2, ECO:0007744|PDB:3WA3 |
| Chain | Residue | Details |
| A | HIS592 | |
| B | HIS431 | |
| B | HIS433 | |
| B | HIS592 | |
| A | HIS431 | |
| A | HIS433 | |
| Chain | Residue | Details |
| A | 2TY382 | |
| B | 2TY382 | |
